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Verapamil and norverapamil in plasma and breast milk during breast feeding (1987)

Anderson, P. ; Bondesson, U. ; Mattiasson, I. ; [et al.]

Springer

European journal of clinical pharmacology 31 (1987), S. 625-627

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ISSN: 1432-1041

Keywords: verapamil ; breast milk ; norverapamil ; breast feeding ; pharmacokinetics

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology , Medicine

Notes: Summary The concentrations of verapamil and norverapamil have been measured in milk and plasma samples from a 32year-old woman treated with verapamil 80 mg tds while breast-feeding her child. The average steady-state concentrations of verapamil and norverapamil in milk were, respectively, 60% and 16% of the concentrations in plasma. The breast-fed child received less than 0.01% of the dose of verapamil given to the mother. No verapamil or norverapamil (〈1 ng/ml) could be detected in the plasma from the child.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00606644

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