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Digitale Medien

New chicken Rfp-Y haplotypes on the basis of MHC class II RFLP and MLC analyses (1997)

Juul-Madsen, H. R. ; Zoorob, Rima ; Auffray, Charles ; [weitere]

Springer

Immunogenetics 45 (1997), S. 345-352

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Details

ISSN: 1432-1211

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin

Notizen: Abstract New chicken Rfp-Y haplotypes were determined by the use of restriction fragment length polymorphism (RFLP) and mixed lymphocyte culture (MLC) in four different chicken haplotypes, B 15 , B 19 , B 21 , B 201 . The RFLP polymorphism was mapped to the Rfp-Y system by the use of a subclone (18.1) which maps near a polymorphic lectin gene located in the Rfp-Y system and DNA from families with known segregation of the implicated RFLP polymorphism. For the first time it is shown that major histocompatibility complex class II genes in the Rfp-Y system have functional implications. Sequence information of the B1 domain of the proposed Rfp-Y haplotypes was obtained which supported the functional data.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/s002510050215

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