ISSN:
1432-1084
Keywords:
Renal artery obstruction
;
Magnetic resonance
;
Blood flow velocity
;
Hypertension, renal
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Three-dimensional (3D) phase-contrast magnetic resonance angiography (MRA) and velocity-encoded cine magnetic resonance (VEC-MR) imaging were performed in 23 subjects to assess the severity of renal artery stenosis. MRA was used for detection of stenosis, demonstrating a sensitivity of 100% and a specificity of 80%; the severity of stenosis was overestimated in 33%. VEC-MR was used to quantify the renal flow oattern and was successful in 11 subjects. Mean blood flow of normal renal arteries (420 +- 107 ml/min) was significantly higher (P 〈 0.01) than mean blood flow of stenotic arteries (131 +- 46ml/min). The flow profile displayed both systolic and diastolic peaks in 75% of the normal arteries, while the flow in stenotic arteries showed only a single systolic peak in all cases. The systolic peak in stenotic arteries occurred significantly later (32 +- 3% of the period of one cardiac cycle) than in normal subjects (21 +- 7%) (P 〈 0.05). Phase-contrast MR is likely to gain considerable importance in the noninvasive aetection and quantification of renal artery stenosis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00169596
