ISSN:
1432-1084
Keywords:
Key words: Magnetic resonance imaging (MRI)
;
Interventional MRI
;
Fibre optics
;
Laser therapy
;
MR-guided therapy
;
Specialised MRI systems
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract. The aim of this study was to develop methods of visualising optical fibres on MRI scans for monitoring interstitial laser therapy. Scans were performed on a specialised MRI extremity scanner at 0.17 T. Optical fibres of 0.4 mm diameter used for delivering laser energy were coated with iron particles from a superferromagnetic contrast agent. MR images of the fibres were acquired using gradient echo sequences (TR/TE = 300/10, 1 mm in-plane, 3 mm slice) and assessed for fibre visibility. Coated fibres could be resolved as lines 2 ± 1 mm wide using the gradient echo sequence. Uncoated fibres were invisible on the sequences used for in vivo therapy monitoring due to partial volume averaging. It is concluded that optical fibre visualisation by MRI may be improved by coating with ferromagnetic particles. Biocompatibility requires further assessment, but direct coating appears to be a promising method for fibre visualisation in MR-guided laser therapy.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s003300050300
