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Nucleus raphe dorsalis in parkinsonism-dementia complex of Guam (1985)

Yamamoto, T. ; Hirano, A.

Springer

Acta neuropathologica 67 (1985), S. 296-299

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ISSN: 1432-0533

Keywords: Parkinsonism-dementia complex of Guam ; Nucleus raphe dorsalis ; Alzheimer's disease ; Morphometry ; Neurofibrillary tangles

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Recently, morphometric analysis has shown that the nucleus raphe dorsalis, which is presumed to project diffuse serotonergic fibers to the telencephalon, is affected in Alzheimer's disease. A similar study was conducted in this report in two patients with parkinsonism-dementia complex of Guam and a Guamanian control. It demonstrated a significant reduction in the number of large neurons, and the presence of abundant Alzheimer's neurofibrillary tangles in this nucleus.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00687815

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