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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 225 (1966), S. 375-383 
    ISSN: 1432-069X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurde der Typ der Antikörper, ob zirkulierende oder gewebsgebundene, erörtert. Die Beobachtungen einiger besonderer Fälle und die Ergebnisse der Epicutantestung sprechen dafür, daß beim FAE gewebsgebundene Antikörper die Hauptrolle spielen. Die histologischen Untersuchungen — in den zeitlich verschiedenen Stadien des FAE durchgeführt — sprechen eher dafür, daß die Antigen-Antikörper-Reaktion in der Cutis und nicht in der Epidermis stattfindet.
    Notes: Summary The authors discuss which type of antibodies, the circulating or the tissue-bound antibodies, are important in the pathogenesis of fixed drug eruptions (FAE). Observation of some pertinent cases and results of epicutaneous tests support the hypothesis that in FDE the tissue-bound antibodies are of main importance. Histologic examinations of different stages of FDE are rather indicative of the antigen-antibody reaction taking place in the cutis, not in the epidermis.
    Type of Medium: Electronic Resource
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