ISSN:
1437-1596
Keywords:
Key words Brain injury
;
Cortical contusion
;
GFAP ¶expression
;
Immunohistochemistry
;
Wound age
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
,
Law
Notes:
Abstract The course of GFAP expression by astrocytes has been immunohistochemically investigated during the first 30 weeks after human brain injury. In order to provide reliable data for a forensic wound age estimation, a quantitative morphometric analysis was performed considering the different topographic regions of the cortex as well as of the white matter. Compared to the GFAP immunoreactivity in unaltered control tissue, significantly increased numbers of GFAP positive astroglial cells could be detected adjacent to the cortical contusion from 1 day up to 4 weeks after brain injury.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/PL00007711
