ISSN:
1432-0770
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Computer Science
,
Physics
Notes:
Abstract An analysis method to detect the presence of feedback between biological signals, particularly those associated with the central nervous system, is presented. The technique is based on recent results in the system identification literature involving the concept of a feedback free process. It may be applied to volume conducted signals such as EEG and EMG, as well as to neuronal spike trains through the use of a data transformation procedure. The utility of the technique is then demonstrated in a study of the relationship between Parkinsonian tremor and certain tremor cells found in the thalamus of Parkinsonian patients, using data collected during thalamotomies. The results obtained suggest that feedback mechanisms may be an important factor contributing to Parkinsonian tremor.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00207288
