ISSN:
1432-2307
Keywords:
Bronchial carcinoids
;
Different types
;
Cells of origin
;
Ultrastructure
;
Histology
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Seven of eleven bronchial carcinoids investigated showed cells with small granules resembling P cells which have already been described in human fetal and adult lung; two of these P cell tumours showed distinctive paraganglioid features. One tumour showed peculiar ultrastructural findings resembling closely those previously reported by Black (1969) in a so called “pulmonary oncocytoma”. Three remaining cases showed large secretory granules resembling those of type 3 cells already described by Hage (1973 b) in bronchial carcinoids; one of these tumours produced large amounts of 5-hydroxytryptamine (5HT). It is concluded that, on cytological grounds, at least two types of tumours can be distinguished among bronchial carcinoids, i.e. P cell and type 3 cell tumours. Moreover, two varieties of P cell carcinoids have been recognized, showing either the less frequent and more distinctive paraganglioid structure or the more common trabecular structure.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00432474
