ISSN:
1432-1076
Keywords:
Respiratory distress syndrome
;
Surfactant protein A
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Surfactant-associated protein (SP-A) was measured in tracheal aspirates of ventilated infants with (n=51) and without (n=21) respiratory distress syndrome (RDS). SP-A concentrations in samples collected after birth were significantly lower in RDS than in infants ventilated for other reasons than RDS (median 0.03 vs. 1.60 μg/ml). As a biochemical test to diagnose RDS early after birth, the sensitivity of measuring SP-A in tracheal aspirates was 87% and specificity 81%. SP-A content in tracheal aspirates of infants with RDS was monitored during the first 7 days of life. A significant (P〈0.001) increase within the first 4 days was found in those infants who survived, whereas no such change was found in those infants who died.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01957730
