ISSN:
1432-1076
Keywords:
Key words Phenylketonuria
;
Intelligence
;
Education
;
Professional career
;
Phenylalanine
;
control
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The intellectual status and professional careers of 51 young adults with phenylketonuria whose treatment started before 3 months of age are described. Their mean IQ was 97 (SD = 16). Of the IQs, 4% were more than 2 SD below the norm. The distribution of types of schooling of the patients was comparable to that in the German population. The professional careers of nearly all the patients were according to their educational level. Within the sample the outcome was significantly correlated with phenylalanine (Phe) control, even when the patients’ social background was statistically taken into account. The main influence of Phe on intelligence seems to occur during the first decade of life since IQ data remain stable even after Phe levels increased during adolescence.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/PL00014262
