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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 82 (1974), S. 257-258 
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die carcinogene Wirkung von N-Nitrosotetrahydrooxazin-1,3 (NTO) wurde an Sprague-Dawley-Ratten untersucht. Bei einer Gabe von 60 mg/kg zweimal pro Woche oral (entsprechend 17 mg/kg täglich) bis zu einer Gesamtdosis von 2,9 g/kg erwies sich NTO als ein starkes Lebercarcinogen mit einer Induktionszeit von 165 ± 13 Tagen.
    Notes: Summary The carcinogenic action of N-Nitroso-tetrahydro-1,3-oxazine (NTO) in Sprague-Dawley rats was investigated. Dosages applied were 60 mg/kg per os twice a week (corresponding to 17 mg/kg daily) up to a total dose of 2,9 g/kg. NTO was found to be a strong liver carcinogen with induction time of 165 ± 13 days.
    Type of Medium: Electronic Resource
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