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Digitale Medien

A male pseudohermaphrodite with a dicentric Y chromosome (1968)

Ferrier, Pierre E. ; Ferrier, Simone A. ; Bill, Alexander H.

Springer

Human genetics 〈Berlin〉 6 (1968), S. 131-141

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Details

ISSN: 1432-1203

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin

Notizen: Summary A 13-year-old male pseudohermaphrodite (mixed gonadal dysgenesis, unilateral testicular differentiation) was found to be a chromosomal mosaic of the 45, XO/46, XY type, the Y chromosome being a symmetrical dicentric chromosome. Presumed Y chromosomes similar to this one have been observed before, but their identification was not supported by autoradiographic data. In the present study the identification of the dicentric as a Y chromosome was supported by observing a relatively late DNA replication during the S period. The differentiation of testicular tissue on one side may be related to the presence of short arm material of the Y chromosome in the genome of the XY dic cells.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00297721

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