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PI LBEI and PI JHOU: two new alpha-1-antitrypsin alleles (1984)

Ying, Qi-long ; Liang, Chih-chuan ; Zhang, Mei-lin

Springer

Human genetics 〈Berlin〉 68 (1984), S. 48-50

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ISSN: 1432-1203

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary Two new variants of alpha-1-antitrypsin were found in a Chinese population by isoelectric focusing in polyacrylamide gel. They have been named Lbeijing (PI*LBEI) and Jhouyao (PI*JHOU) respectively. With the samples reduced and alkylated, both the variants were anodal to M1 and cathodal to L. Omitting the alkylation step, however, the relative mobilities of L and Jhouyao were altered. Under this condition, a characteristic of Jhouyao was revealed by isoelectric focusing in immobilized pH gradient 4.4–4.9, i.e., while its band 6 became anodal to L, band 4 was still cathodal to L.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00293870

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