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Observations on the ultrastructure of microtubules (1971)

Olson, L. W. ; Heath, I. B.

Springer

Cell & tissue research 115 (1971), S. 388-395

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ISSN: 1432-0878

Keywords: Microtubule ; Ultrastructure ; Spindle ; Flagellum ; Subunit

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary After a specific time of glutaraldehyde-acrolein fixation, microtubule walls appear to be composed of single 6.5–7.5 nm diameter osmiophilic subunits. Variations in the duration of glutaraldehyde-acrolein and also glutaraldehyde-osmium fixation reveal a two layered wall containing osmiophilic subunits, 4.0–4.5 nm in diameter, arranged radially, in tandem. The double-layered wall is demonstrated by microdensitometer traces. These observations are discussed in relation to previously proposed models of microtubule substructure.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00324941

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