ISSN:
1435-1536
Keywords:
Multichain copoly(α-amino acid)
;
Conformational transition
;
Helix conformation
;
Optical Rotatory Dispersion
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Abstract The conformational transition of multichain copoly(α-amino acid)s consisting of copoly(γ-methyl-L-glutamyl-L-lysine) as backbone molecule and poly(γ-benzyl-L-glutamate) as branch molecules was studied in chloroform and DCA mixtures. The helix stability of backbone molecule is strongly affected by the length of branch molecules. In the case of the multichain copolymer having short branch molecular chains, i.e.,DP br 〈10, the helix conformation of the backbone molecule is strictly affected by some interferences among the randomly coiled molecular chains. In the case of water-soluble multichain copolymer having poly(L-glutamic acid) or poly(L-lysine) as branch molecules, the transitional process from coil to helix is observed by depressing hydrostatic repulsion among the ionized side chain of branch molecules. However, such conformational transition is depressed to a considerable extent by interferences among the branch molecules.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01410262
