ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] To test the functional consequences of abolishing tyrosine kinase activity with minimal structural alterations in the EGF receptor, the lysine at position 721 was mutated to a methionine. This amino acid, conserved amongst all the protein kinase family members, is thought to provide a salt bridge ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/328820a0