ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
The porous scaffolds of silk fibroin-chitosan /nano-hydroxyapatite (SF-CS / n-HA) werefabricated through the freeze- drying technique. Component, structure and morphology of scaffoldswere studied by infrared (IR), X-ray diffusion (XRD) and scanning electron microscope (SEM), andthe mechanical properties of the scaffolds were measured. The simulated body fluid (SBF)experiments were conducted to assess the bioactivity of the scaffolds. Results indicate that chemicalbinding is formed between HA and organics, the macropore diameter of the scaffolds varies from150 to 400μm. The porous scaffolds with interconnected pores possess a high porosity of 78%-91%and compressive strength of 0.26 -1.96MPa, which can be controlled by adjusting the concentrationof organic phases and prefreezing temperature. In the SBF tests, a layer of randomly orientedbone-like apatite crystals formed on the scaffold surface, which suggested that the compositematerial had good bioactivity. Studies suggest the feasibility of using SF-CS /n-HA compositescaffolds for bone tissue engineering
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/53/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.330-332.971.pdf
