ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
We have developed a porous titanium implant sintered with spacer particles (porosity =50 %, average pore size ± standard deviation = 303 ± 152 !m, yield compression strength = 100MPa).This porous titanium was successfully treated with chemical and thermal treatment that gives abioactive micro-porous titania layer on the titanium surface, and it is expected as effective biomaterialfor biological fixation on load bearing condition. In this study, ten adult female beagle dogsunderwent anterior lumbar interbody fusion at L6-7 using either BT-implant or non-treated implant(NT-implant), then followed by posterior interspinous wiring and facet screw fixation. Theradiographic evaluations were performed 1, 2 and 3 months postoperatively using X-ray fluoroscopy.Animals were sacrificed after 3 months postoperatively, and fusion status was evaluated by manualpalpation. Histological evaluation was also performed. Both histological and radiological evaluationrevealed that interbody fusion was achieved in 5 of 5 dogs (100%) in BT-group and 3 of 5 dogs (60%)in NT-group. In BT implants, we could observe a large amount of new bone formation from peripheryto the center of the implant, whereas in NT implants, fibrous tissue formation was still observed evenin the implants with successful fusion. The results of this study indicate that porous bioactive titaniumimplant will represent a new osteoconductive biomaterial with improved fusion characteristics
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/53/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.330-332.987.pdf
