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Respiratory disease due to sulphasalazine (1974)

THOMAS, PETER ; SEATON, ANTHONY ; EDWARDS, JOHN

Oxford, UK : Blackwell Publishing Ltd

Clinical & experimental allergy 4 (1974), S. 0

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ISSN: 1365-2222

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: A patient is described who developed a pulmonary hypersensiiivity reaction to sulphasalatzine used in the treatment of his ulcerative colitis. Challenge testing demonstrated that the patient was sensitive to the sulphapyridine component of the drug. The pulmonary response consisted of an immediate bronchial obstructive reaction and a late parenchymal reaction with fall in gas transfer factor. Detailed immunological testing failed to define the mechanisms of drug toxicity.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1365-2222.1974.tb01361.x

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