Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
British journal of dermatology
80 (1968), S. 0
ISSN:
1365-2133
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
SUMMARY. —Beclomethasone dipropionate is a new topical steroid with marked vasoconstrictor and anti-inflammatory activity. At a concentration of 0·025% in a simple, oil-in-water emulsion “cream” base beclomethasone dipropionate is significantly more effective clinically than is fluocinolone acetonide 0·025%) in an apparently similar base. The effectiveness of beclomethasone dipropionate 0·025% in an ointment base is significantly increased by dissolving the steroid in propylene glycol before incorporating it into the ointment. Beclomethasone dipropionate 0·025% in a propylene glycol/ointment base is clinically indistinguishable from fluocinolone acetonide 0·025% ointment. Further investigation of the influence of cream and ointment bases on the clinical effectiveness of topical steroids might prove interesting.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2133.1968.tb12270.x
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