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The influence of age on the onset of anaesthesia with midazolam (1985)

DUNDEE, J. W. ; HALLIDAY, N. J. ; LOUGHRAN, P. G. ; [et al.]

Oxford, UK : Blackwell Publishing Ltd

Anaesthesia 40 (1985), S. 0

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ISSN: 1365-2044

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: There was a considerable individual variation in response to a standard induction dose of 0.3 mg/kg midazolam in unpremedicated patients. This is shown by variations in time to onset of sleep and the fact that about one quarter of subjects did not lose consciousness in 3 minutes. In 166 fit patients a good negative correlation was demonstrated between the age of the patients and time to loss of consciousness. Patients over 50 years differed from younger patients in a greater reliability of effect and significantly shorter induction time. In elderly patients midazolam is a more reliable induction agent than in the young.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1365-2044.1985.tb10845.x

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