Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Australasian journal of dermatology
32 (1991), S. 0
ISSN:
1440-0960
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
A review of consecutive biopsies from 85 Malaysian patients with primary localized cutaneous amyloidosis (PLCA) revealed 63 with papular amyloidosis (PA) and 22 with macutar amyloidosis (MA). PLCA appeared to affect the Chinese more frequently than the other major ethnic groups but MA was more common than expected among the Indians. Of patients with PA, one had systemic lupus erythematosus, one scleroderma and in another, connective tissue disease was suspected. MA was not found to be associated with any other disease.Histologically, PA differed from MA by the larger size of amyloid deposits in the papillary dermis. There was no difference in their tinctorial and immunohistochemical characteristics. Deposits were permanganate-resistant and negative for AA protein, immunoglobulin light chains and keratin. A few cases exhibited positively for cytokeratin. Strong immunoreactivity for AP protein was observed. PA and MA appear chemically similar and are likely to be of epidermal origin.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1440-0960.1991.tb00681.x
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