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Serum lactate dehydrogenase levels in malignant germ cell tumors of ovary (1996)

Patel, P.S. ; Sharma, V.M. ; Raval, G.N. ; [et al.]

Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Science Inc.

International journal of gynecological cancer 6 (1996), S. 0

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ISSN: 1525-1438

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Serum lactate dehydrogenase (LDH) levels were examined in 24 patients with germ cell tumors of the ovary to evaluate the usefulness of the enzyme as a tumor maker. Lactate dehydrogenase levels were found to be significantly elevated (P 〈 0.001) in these patients at the time of diagnosis as compared to the controls. Lactate dehydrogenase levels in patients with benign ovarian tumors and controls were comparable. The positive rate of LDH for malignant germ cell tumors of the ovary was 94.5%. The LDH values significantly declined in the patients who responded to treatment. Metastatic or recurrent disease resulted in increased LDH levels. The results indicate that LDH is a useful tumor marker for malignant germ cell tumors of the ovary.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1046/j.1525-1438.1996.06040328.x

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