ISSN:
1365-3083
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
The level of α1FP has been evaluated in the sera of 155 children aged 1 month to 16 years with germ cell tumors. Abnormal α1FP levels were found in 63 cases.Reexamination of histological slides from more than 120 cases, in a double blind study has revealed a close connection between the presence of abnormal α1FP levels in the serum and the presence of vitelline components on the tissue sections: 54 yolk sac tumor out of 60 are α1FP positive (that is 90% and 100% in the acute phase), whatever the site: testis, ovary, vagina, sacrococcygeal, intra- or retro-peritoneal region, mediastinum or intracranium.Immunohistological localization (immuno-fluorescence and immuno-peroxydase) was performed in this study.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-3083.1978.tb03921.x
