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Neutrophil Chemotaxis Defect in IgA Deficiency Evaluated by Migration Agarose Method (1980)

D'AMELIO, R. ; LeMOLI, S. ; ROSSI, P. ; [et al.]

Oxford, UK : Blackwell Publishing Ltd

Scandinavian journal of immunology 11 (1980), S. 0

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ISSN: 1365-3083

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: The chemotactic and random mobility functions of twelve selectively IgA-deficient patients were evaluated by a method using agarose gel. A severe polymorphonuclear cellular chemotactic defect was found in ten out of twelve patients, but only five of them also showed a marked associated impairment of random locomotory function. Furthermore, in one subject, levamisole therapy resulted in a dramatic improvement of both chemotactic and random mobility functions. These results are discussed in the paper with respect to the possible pathogenetic implications.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1365-3083.1980.tb00015.x

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