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  • 11
    Electronic Resource
    Electronic Resource
    Mixed chemodectoma-ganglioneuroma of the conus medullaris region (1982)
    Springer
    Acta neuropathologica 57 (1982), S. 275-281 
    Details
    ISSN: 1432-0533
    Keywords: Spinal cord ; Conus medullaris ; Mixed chemodectoma and ganglioneuroma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Report of a 33-year-old man with a yearlong historory of low-back pain radiating into the left leg. Neurologic examination upon admission tto the hospital revealed a spinal compression syndrome at the lovel L5. Laminectomy at L4/5 revealed an encapsulated intradural tumor measuring 4×2.5×2.5 cm. The tumor was attached to the dorsal root L4 and extended downward to the conus region. Light and electron microscopy revealed features mostly consistent with a mixed chemodectoma and ganglioneuroma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00692183
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  • 12
    Electronic Resource
    Electronic Resource
    Dielectric properties of thin sections of barium titanate ceramics (1981)
    Springer
    Applied physics 25 (1981), S. 195-200 
    Details
    ISSN: 1432-0630
    Keywords: 77
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Thin sections in the thickness range down to 3–5 μm were produced from bariumtitanate ferroelectric ceramics. The small signal dielectric constant, as well as hysteresis loops were measured. Significant deviations from the bulk properties were observed, when the thickness of the sample was decreased to the average diameter of the grains. The measured results are discussed proposing a model with internal stresses and a distorted surface layer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00902972
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  • 13
    Electronic Resource
    Electronic Resource
    High-dose ketoconazole (HD-KNZ) in the initial treatment of leucopenic patients with fever (1984)
    Springer
    European journal of pediatrics 143 (1984), S. 73-73 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442755
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  • 14
    Electronic Resource
    Electronic Resource
    Caring of the nails and anticancer treatment (1984)
    Springer
    European journal of pediatrics 143 (1984), S. 74-74 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442756
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  • 15
    Electronic Resource
    Electronic Resource
    Interaction between mianserin and clonidine at α 2-Adrenoceptors (1982)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 318 (1982), S. 288-294 
    Details
    ISSN: 1432-1912
    Keywords: Mianserin ; Clonidine ; Desipramine ; Acetylcholine ; α2-Adrenoceptors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The purpose of the present study was to characterize the effects of mianserin at α2-adrenoceptors. Firstly, the action of mianserin on postganglionic sympathetic fibres has been studied using the tachycardia induced by stimulation of the cardiac nerve in dogs. Mianserin increased this tachycardia, but could not prevent the inhibitory effect of clonidine in this model. However, an antagonistic effect of mianserin against clonidine was observed when animals were pretreated with desipramine. Secondly, mianserin antagonized the inhibitory effect of clonidine on the electrically stimulated guinea-pig ileum. In high concentrations, mianserin reduced both electrically and acetylcholine induced contractions. Thirdly, mianserin antagonised the sleep induced by clonidine in chickens. These results are consistent with α2-adrenoceptor blocking properties of mianserin in peripheral noradrenergic fibres in dogs, in cholinergic fibres in guinea-pig ileum and in the central nervous system in chickens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00501167
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  • 16
    Electronic Resource
    Electronic Resource
    A hybrid DNA sequence containing the replication origin of the multicopy yeast plasmid 2 μm circle and an additional repeated sequence can convert maltose-negative into maltose-positive strains (1984)
    Springer
    Molecular genetics and genomics 197 (1984), S. 491-496 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Yeast DNA pools were prepared by ligating partial Sau3A genomic digests from strains carrying various MAL genes into the BamHI site of the yeast-Escherichia coli shuttle vector YRp7. They were used to transform recipient yeast strains that could not utilize maltose since they lacked a classical MAL gene. Transformants were obtained that could use maltose and also formed normal levels of maltase. They were unstable. They would lose the selective marker TRP1 of YRp7 alone, together with the ability to utilize maltose or only the ability to utilize maltose. The insertion of one of the plasmids was used as a hybridization probe for the others and found to share homologous sequences with all. They were then shown to contain the replication origin of the yeast 2 μm circle plasmid and additional genomic digests of total yeast DNA. They hybridized at various degrees of efficiency with several bands, indicating that they were part of a family of repeated sequences. Apparently, it was the combination of the replication origin of the 2 μm circles with the additional sequences that promoted maltose utilization.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00329948
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  • 17
    Electronic Resource
    Electronic Resource
    Genetic and physiological evidence for the existence of a second glycolytic pathway in yeast parallel to the phosphofructokinase-aldolase reaction sequence (1984)
    Springer
    Molecular genetics and genomics 195 (1984), S. 536-540 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Yeast mutants lacking phosphofructokinase activity because of a defect in one of the two genes PFK1 and PFK2 can still perform glycolysis and produce ethanol. However, they differ from normal wild-type yeast in several ways. After a transfer from a sugar-free to a glucose medium, wild-type cells start to produce ethanol right away, mutants only after a lag period of about 90 min. About two-thirds of the carbon atoms released as CO2 from wild-type cells derive from glucose carbon atoms 3 and 4. Mutants with a single defect in one of the two phosphofructokinase genes PFK1 and PFK2 show no such a preferential contribution of these two C-atoms of glucose. All six C-atoms contribute almost equally to CO2 production. We have isolated mutants that block glycolysis in single pfk1 and pfk2 mutants. They could be located in three different genes called BYP1, BYP2 and BYP3 (BYP for bypass). In a byp1 mutant, CO2 derived almost exclusively from C-atoms 3 and 4 of glucose. This is what the classical concept of yeast glycolysis predicts. During a search for metabolites accumulating in pfk and byp mutants, we found sedoheptulose-7-phosphate, a pentosephosphate cycle intermediate not detectable in wild-type cells. An analysis of enzymes acting in the direct oxidation of glucose-6-phosphate and in the pentosephosphate cycle did not show any defects in those activities. It is hypothesized that the pentosephosphate cycle not only functions, in providing phosphorylated derivatives of tetroses and pentoses for biosynthetic needs, but also plays an important role in sugar catabolism and fermentation. This hypothesis also implies that the reaction sequency catalyzed by phosphofructokinase and aldolase covers only part of the total catabolic flux.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00341459
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  • 18
    Electronic Resource
    Electronic Resource
    Yeast mutants without phosphofructokinase activity can still perform glycolysis and alcoholic fermentation (1984)
    Springer
    Molecular genetics and genomics 195 (1984), S. 530-535 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Mutants of Saccharomyces cerevisiae without detectable phosphofructokinase activity were isolated. They were partly recessive and belonged to two genes called PFK1 and PFK2. Mutants with a defect in only one of the two genes could not grow when they were transferred from a medium with a nonfermentable carbon source to a medium with glucose and antimycin A, an inhibitor of respiration. However, the same mutants could grow when antimycin A was added to such mutants after they had been adapted to the utilization of glucose. Double mutants with defects in both genes could not grow at all on glucose as the sole carbon source. Mutants with a single defect in gene PFK1 or PFK2 could form ethanol on a glucose medium. However, in contrast to wild-type cells, there was a lag period of about 2 h before ethanol could be formed after transfer from a medium with only nonfermentable carbon sources to a glucose medium. Wild-type cells under the same conditions started to produce ethanol immediately. Mutants with defects in both PFK genes could not form ethanol at all. Mutants without phosphoglucose isomerase or triosephosphate isomerase did not form ethanol either. Double mutants without phosphofructokinase and phosphoglucose isomerase accumulated large amounts of glucose-6-phosphate on a glucose medium. This suggested that the direct oxidation of glucose-6-phosphate could not provide a bypass around the phosphofructokinase reaction. On the other hand, the triosephosphate isomerase reaction was required for ethanol production. Experiments with uniformly labeled glucose and glucose labeled in positions 3 and 4 were used to determine the contribution of the different carbon atoms of glucose to the fermentative production of CO2. With only fermentation operating, only carbon atoms 3 and 4 should contribute to CO2 production. However, wild-type cells produced significant amounts of radioactivity from other carbon atoms and pfk mutants generated CO2 almost equally well from all six carbon atoms of glucose. This suggested that phosphofructokinase is a dispensable enzyme in yeast glycolysis catalyzing only part of the glycolytic flux.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00341458
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  • 19
    Electronic Resource
    Electronic Resource
    Die Verantwortung des HNO-Arztes bei der Erkennung des Olfaktoriusmeningeoms (1981)
    Springer
    European archives of oto-rhino-laryngology and head & neck 231 (1981), S. 756-756 
    Details
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00501732
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  • 20
    Electronic Resource
    Electronic Resource
    Measurement ofj/ψ-decays into channels containing charged and neutral antinucleons (1981)
    Springer
    The European physical journal 8 (1981), S. 1-5 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Using the nonmagnetic BONANZA detector for the detection of antineutrons and antiprotons, we measured branching ratios of theJ/ψ into baryonic final states. Our measurements give the new results: $$BR\left( {{J \mathord{\left/ {\vphantom {J {\psi \to \overline {\Sigma ^ - } }}} \right. \kern-\nulldelimiterspace} {\psi \to \overline {\Sigma ^ - } }}\Sigma ^ - } \right) = \left( {0.24 \pm 0.26} \right)\% ;BR\left( {{J \mathord{\left/ {\vphantom {J {\psi \to }}} \right. \kern-\nulldelimiterspace} {\psi \to }}\bar nn\pi ^ + \pi ^ - } \right) = \left( {0.38 \pm 0.36} \right)\% $$ and an independent test for the data of the magnetic detectors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01429822
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