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  • Articles: DFG German National Licenses  (20)
  • 1995-1999  (20)
  • 1985-1989
  • 1960-1964
  • 1997  (8)
  • 1996  (12)
  • 11
    Electronic Resource
    Electronic Resource
    An unusual cervical chordoma: CT and MRI (1996)
    Springer
    Neuroradiology 38 (1996), S. 466-467 
    Details
    ISSN: 1432-1920
    Keywords: Cervical chordoma ; Magnetic resonance imaging ; Computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report CT and MRI findings of an unusual cervical chordoma. CT showed only minimal bony destruction with a lobulated prevertebral mass. Sagittal MRI, however, clearly demonstrated a lesion involving the body of C2 extending prevertebrally and into the spinal canal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00607279
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    Paper (German National Licenses)
    Fulltext
  • 12
    Electronic Resource
    Electronic Resource
    An unusual cervical chordoma: CT and MRI (1996)
    Springer
    Neuroradiology 38 (1996), S. 466-467 
    Details
    ISSN: 1432-1920
    Keywords: Key words Cervical chordoma ; Magnetic resonance imaging ; Computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report CT and MRI findings of an unusual cervical chordoma. CT showed only minimal bony destruction with a lobulated prevertebral mass. Sagittal MRI, however, clearly demonstrated a lesion involving the body of C2 extending prevertebrally and into the spinal canal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00607279
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    Paper (German National Licenses)
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  • 13
    Electronic Resource
    Electronic Resource
    The main HTLV-I-harboring cells in the muscles of viral carriers with polymyositis are not macrophages but CD4+ lymphocytes (1996)
    Springer
    Acta neuropathologica 92 (1996), S. 358-361 
    Details
    ISSN: 1432-0533
    Keywords: Key words In situ polymerase chain reaction ; Immunohistochemistry ; Human T cell lymphotropic ; virus type I ; Proviral DNA ; Polymyositis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have analyzed muscle biopsy specimens from polymyositis patients who are also positive for human T cell lymphotropic virus type I (HTLV-I) using both immunohistochemistry for surface antigens of lymphocytes and macrophages and in situ polymerase chain reaction for HTLV-I proviral DNA on the same sections. We found HTLV-I in CD4+ cells but not in macrophages. This finding suggests that most of the HTLV-I-containing CD4+ cells are not macrophages but lymphocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010050530
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    Paper (German National Licenses)
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  • 14
    Electronic Resource
    Electronic Resource
    Age-related changes in the compound action potentials of the eighth nerve in guinea pigs (1997)
    Springer
    European archives of oto-rhino-laryngology and head & neck 254 (1997), S. 145-149 
    Details
    ISSN: 1434-4726
    Keywords: Eighth nerve compound action potential ; Aging effects ; Guinea pig
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The eighth nerve compound action potential (CAP) in 95 guinea pigs was measured using click stimuli to investigate age-related changes in their neural auditory thresholds. The animals were separated into three groups: group A (n = 43, 86 ears; 2–4 months old); group B (n = 29; 58 ears, 13–15 months old); and group C (n = 23; 46 ears, 23–25 months old). With increasing age, a gradual elevation of CAP thresholds was clearly seen among the three groups. The negative peak (N1) latencies of the CAP were prolonged, and the N1 amplitudes of the CAP decreased. There were significant differences in N1 latencies among the three groups and in N1 amplitudes between groups A and B, and between groups A and C. However, the rate of decline of the thresholds as well as the input-output function curves of the CAP varied in some of the oldest animals, suggesting that there were some individual differences in degenerative aging processes of the auditory system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02471279
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    Paper (German National Licenses)
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  • 15
    Electronic Resource
    Electronic Resource
    Production method of no-carrier-added186Re (1996)
    Springer
    Journal of radioanalytical and nuclear chemistry 205 (1996), S. 85-92 
    Details
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract No-Carrier-Added186Re was produced using the186W(p,n)186Re nuclear reaction with 13.6 MeV protons on thick targets of 99.79% isotopically enriched186WO3. The theoretical excitation functions for producing186Re, and possible radionuclidic impurities of182Re,183Re, and184Re were calculated using the ALICE code. Cross-sections of the186W(p,n)186Re reaction were measured up to 20 MeV using the stacked target method with thin foils of natural composition tungsten metal. The experimental and theoretical excitation functions were in good agreement. Targetry used at the TIARA cyclotron, and a radiochemical separation scheme for186Re are described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02040553
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    Paper (German National Licenses)
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  • 16
    Electronic Resource
    Electronic Resource
    Surface activation of manganese oxide electrode for oxygen evolution from seawater (1997)
    Springer
    Journal of applied electrochemistry 27 (1997), S. 1362-1368 
    Details
    ISSN: 1572-8838
    Keywords: manganese oxide electrode ; oxygen evolution ; seawater electrolysis ; surface activation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract Utilizing the fact that the equilibrium potential of oxygen evolution is lower than that of chlorine evolution, oxygen evolution in seawater electrolysis was enhanced by decreasing the polarization potential under galvanostatic conditions through increasing the effective surface area of manganese oxide electrodes. Electrodes were prepared by a thermal decomposition method. IrO2-coated titanium (IrO2/Ti electrode) was used as the substrate on which manganese oxide was coated (MnOX/IrO2/Ti electrode). Subsequently, oxide mixtures of manganese and zinc were coated (MnOX–ZnO/MnOX/IrO2/Ti electrode). The effective surface area of the MnOX–ZnO/MnOX/IrO2/Ti electrodes was increased by selective dissolution of zinc (leaching) into hot 6M KOH. The oxygen evolution efficiency of the MnOX/IrO2/Ti electrode was 68–70%. Leaching of zinc from the MnOX–ZnO/MnOX/IrO2/Ti electrodes with 25mol% or less zinc led to a significant increase in the oxygen evolution efficiency. The maximum efficiency attained was 86% after leaching of zinc from the MnOX–25mol%ZnO/MnOX/IrO2/Ti electrode. However, large amounts of zinc addition, such as 40mol% or more are detrimental because of a decrease in the oxygen evolution efficiency. This is due to the formation of a double oxide, ZnMnO3, which is hardly dissolved in hot 6M KOH.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018421028624
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    Paper (German National Licenses)
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  • 17
    Electronic Resource
    Electronic Resource
    Lactoferrin-mediated protection of the host from murine cytomegalovirus infection by a T-cell-dependent augmentation of natural killer cell activity (1996)
    Springer
    Archives of virology 141 (1996), S. 1875-1889 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The administration of bovine lactoferrin (LF) with 1 mg/g body weight before the murine cytomegalovirus (MCMV) infection completely protected the BALB/c mice from death due to the infection. In these LF-treated mice, a significant increase in the activity was found in the NK cells but not in the cytolytic T lymphocytes which recognized an MCMV-derived peptide. Moreover, the elimination of the NK cell activity by an injection with anti-asialo GM1 antibody abrogated such augmented resistance, thus supporting the hypothesis that the LF-mediated antiviral effect in vivo is performed through the augmentation of NK cell activity. No such LF-mediated antiviral effect in vivo with the increased NK cell activity was found in athymic nude mice, whereas it was restored completely by the transfer of splenic T cells from LF-treated donors. These findings therefore suggest that T lymphocytes induce both the augmentation of NK cell activity and the resultant antiviral effect in the LF-treated hosts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01718201
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    Paper (German National Licenses)
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  • 18
    Electronic Resource
    Electronic Resource
    Heat shock induces HIV-1 replication in chronically infected promyelocyte cell line OM10.1 (1996)
    Springer
    Archives of virology 141 (1996), S. 439-447 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A long period of clinical latency before development of symptoms is characteristic of human immunodeficiency virus type 1 (HIV-1) infection. OM10.1, a promyelocyte cell line latently infected with HIV-1, has been developed as a model for studying the mechanism of viral latency and the activation of virus expression. We found that this latently infected cell line with heat shock at 42°C for 2 h resulted in a high level of HIV-1 production without addition of any cytokines. The mechanism of activation was analyzed by using anti-TNF-α antibody and various inhibitors. Although the TNF-α level in culture supernatants was below the sensitivity of an ELISA assay system, addition of anti-TNF-α antibody in culture medium could partially suppress the heat shock induced HIV-1 production. Staurosporine (PKC inhibitor), pentoxifylline (NF-ϰB inhibitor), and Ro5-3335 (HIV-1 Tat inhibitor) also inhibited significantly the heat shock induced virus activation. In particular, staurosporine achieved approximately 90% inhibition of the HIV-1 antigen expression in heat shock-treated OM10.1 at a non-toxic concentration. Although the mechanism of HIV-1 activation with heat shock has not been fully elucidated yet, it is presumed PKC plays an important role in HIV-1 activation. Thus, the present observations will provide a further insight into the pathogenesis of HIV-1 infections.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01718308
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    Paper (German National Licenses)
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  • 19
    Electronic Resource
    Electronic Resource
    Mitochondrial DNA and nuclear DNA indicate that the Japanese Fasciola species is F. gigantica (1997)
    Springer
    Parasitology research 83 (1997), S. 220-225 
    Details
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract For elucidation of the taxonomic status of the Japanese Fasciola species, whole mitochondrial DNA of Fasciola hepatica from Australia, F. gigantica from Malaysia, and Fasciola sp. from Japan was digested with three four-base-cutting endonucleases: HinfI, MspI, and RsaI. The resulting digestion patterns showed that for each enzyme there were some bands specific for each geographical isolate and that the Japanese Fasciola sp. shared more bands with F. gigantica than with F. hepatica. Nucleotide sequences of two regions, the second internal transcribed spacer (ITS2) of the nuclear ribosomal RNA cluster and mitochondrial cytochrome c oxidase subunit I (COI), were also compared among them. The ITS2 sequence was highly conserved among the three isolates. F. gigantica and the Japanese Fasciola sp. were identical, but they differed from the Australian F. hepatica at six sites, one of which was a deletion. The COI sequence was less conserved but implied a similar relationship between the isolates. There seems no reason to regard the Japanese Fasciola sp. as anything other than a strain of F. gigantica.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004360050237
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  • 20
    Electronic Resource
    Electronic Resource
    Anti-neutrophil cytoplasmic antibody in patients with systemic lupus erythematosus is unrelated to clinical features (1997)
    Springer
    Clinical rheumatology 16 (1997), S. 70-75 
    Details
    ISSN: 1434-9949
    Keywords: Disease Activity Index ; Anti-Myeloperoxidase Antibody ; Anti-Lactoferrin Antibody ; Lupus Nephritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To investigate the incidence, the specificity and clinical significance of positivity for serum anti-neutrophil cytoplasmic antibody (ANCA) in 31 patients with systemic lupus erythematosus (SLE), the indirect immunofluorescence (IIF) technique and enzyme-linked immunosorbent assay (ELISA) were used to measure ANCA. Purified myeloperoxidase (MPO), lactoferrin (LF), cathepsin-G (CTG) and elastase (HLE) served as ANCA antigens for ELISA. Thirteen (42%) of the 31 SLE patients showed positivity for perinuclear, but not cytoplasmic, ANCA by IIF. Five of 31 sera were positive for MPO, 10 for LF, 1 for CTG and 0 for HLE by ELISA. Patients positive for ANCA had a higher score of SLE disease activity index (SLEDAI) than those without ANCA. There was no correlation between ANCA positivity, clinical manifestations, or organic involvement. While the ANCA in patients with SLE reflected disease activity, it was unrelated to organic involvement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02238766
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    Paper (German National Licenses)
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