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  • Articles: DFG German National Licenses  (33)
  • 2005-2009  (5)
  • 1990-1994  (28)
  • 1
    Electronic Resource
    Electronic Resource
    Spontaneous alloying of copper atoms into gold clusters at reduced temperatures (1993)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 73 (1993), S. 1100-1103 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The alloying behavior of copper atoms into gold clusters at temperatures lower than 300 K was examined using a 200 kV transmission electron microscope equipped with a double source evaporator in the specimen chamber. Isolated gold clusters of about 4 nm in mean diameter were prepared on a supporting film and were cooled down to 245, 215, 165, or 125 K. Copper atoms were then deposited onto the same film. Upon the deposition of copper, the gold clusters quickly changed into completely or partially alloyed clusters, depending upon the substrate temperature. The copper diffusivity estimated from such spontaneous alloying was many orders of magnitude faster than that in bulk gold. A possible mechanism behind the spontaneous alloying is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.353272
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Interaction of interferon gamma and CPT-11, a new derivative of camptothecin, in human endometrial carcinoma cell lines (1993)
    238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Scientific Publications
    International journal of gynecological cancer 3 (1993), S. 0 
    Details
    ISSN: 1525-1438
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The anti-proliferative effects of interferon gamma (IFN-γ) and CPT-11, a new derivative of camptothecin, both singly and in combination, on two human endometrial carcinoma cell lines, HHUA and ISHIKAWA, were examined in vitro. The HHUA cells were responsive dose-dependently to IFN-γ, while the ISHIKAWA cells were unresponsive to IFN-γ. Both cell lines were responsive dose-dependently to CPT-11. In both cell lines, IFN-γ at clinically achievable concentrations (10 and 100 U ml−1 enhanced the anti-proliferative activity of CPT-11 in the range of concentrations where CPT-11 showed more than 10% cell growth inhibition. Sequential treatment with CPT-11 followed by incubation with IFN-γ resulted in significant cell growth inhibition, but not vice versa. Flow cytometric studies indicated that the combined anti-proliferative effect did not correlate with cytokinetic alterations. Treatment with IFN-γ did not change the extractable topoisomerase I activity of the HHUA and ISHIKAWA cells. The combination therapy of IFN-γ and CPT-11 could provide a new approach against endometrial cancer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1525-1438.1993.03010036.x
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  • 3
    Electronic Resource
    Electronic Resource
    Alloying behavior of gold atoms into nm-sized copper clusters (1992)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 61 (1992), S. 2173-2174 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Alloying behavior of gold atoms into copper clusters has been studied using a 200 kV transmission electron microscope (TEM) equipped with a double source evaporator in the specimen chamber. Isolated copper clusters of approximately 4 nm in diameter were first prepared on a supporting film of amorphous carbon, and then gold atoms were deposited onto the same film kept at room temperature. Upon the deposition of gold, the copper clusters quickly changed into homogeneously mixed Cu-Au alloy clusters. The gold diffusivities in the clusters estimated from the experimental results are at least 19 orders of magnitude faster than those in the bulk copper.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.108285
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Stable cw operation at room temperature of a 1.5-μm wavelength multiple quantum well laser on a Si substrate (1992)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 60 (1992), S. 472-473 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Room-temperature cw operation of an InGaAs/InGaAsP multiple quantum well (MQW) laser diode on a Si substrate is reported. The MQW laser emits at a 1.54 μm wavelength and exhibits no degradation after over 2000 h of operation. Employing a hybrid organometallic vapor phase epitaxy/vapor mixing epitaxy method and a layer structure for improving crystalline quality, high-quality MQW layers are obtained. A stable longitudinal mode spectrum demonstrates the effectiveness of the MQW active layer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.106638
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  • 5
    Electronic Resource
    Electronic Resource
    InAlAs/InGaAs metal-semiconductor-metal photodiodes heteroepitaxially grown on Si substrates (1994)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 64 (1994), S. 751-753 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: To study performance and reproducibility of photodiodes (PDs) on Si in the long-wavelength region, InAlAs/InGaAs metal-semiconductor-metal PDs were fabricated on high-quality heteroepitaxial InP layers on Si substrates. A dark current of 0.5–2×10−8 A and a responsivity of 0.05–0.15 A/W were reproducibly obtained, at least at one of the ±5 V bias voltages. These dark currents and responsivity are similar to those of PDs with the same structure fabricated on InP substrates. The PDs on Si have pulse responses with full widths at half-maximum of 150–600 ps.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.111055
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  • 6
    Electronic Resource
    Electronic Resource
    Outcome of fertility-preserving treatment in young women with endometrial carcinomas (2005)
    Oxford, UK and Malden, USA : Blackwell Science Ltd
    BJOG 112 (2005), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective  To evaluate the outcome of conservative treatment of young women with endometrial cancer.Design  Observational study.Setting  Gifu University Hospital, Japan from 1988 to 2002.Population  Twelve women with endometrial cancer, FIGO IA estimated by MRI under 35 years.Methods  Patients were treated with medroxyprogestreone acetate (400–600 mg/day) for 6–10 months, with endometrial curettage performed every four weeks.Main outcome measures  Response to therapy, pregnancies and reoccurrence of disease during follow up over a 30-month period.Results  All cases had pathological complete remissions within 6–10 months. Seven of 10 wishing to have babies conceived, and five of them were delivered of full-term babies. Eight of nine cases receiving long term follow up (over 30 months) developed recurrent disease, with four opting for hysterectomy. No patient developed distant metastases or had disease-related death.Conclusion  Conservative therapy is feasible in carefully selected young women with endometrial cancer. Recurrence rates were high during long term observation even after pathological complete remissions. Therefore, close follow up is recommended.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.2004.00398.x
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Regulation of the Heat-Shock Response in Bacteria (1993)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Microbiology 47 (1993), S. 321-350 
    Details
    ISSN: 0066-4227
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.mi.47.100193.001541
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  • 8
    Electronic Resource
    Electronic Resource
    An organic thyristor (2005)
    [s.l.] : Nature Publishing Group
    Nature 437 (2005), S. 522-524 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Thyristors are a class of nonlinear electronic device that exhibit bistable resistance—that is, they can be switched between two different conductance states. Thyristors are widely used as inverters (direct to alternating current converters) and for the smooth control of power in a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature04087
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Biological activity of enantiomerically pure forms of insect juvenile hormone I and III inBombyx mori (1990)
    Springer
    Cellular and molecular life sciences 46 (1990), S. 220-221 
    Details
    ISSN: 1420-9071
    Keywords: Juvenile hormone ; enantiomer ; biological activity ; Bombyx mori ; allatectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Biological activity of enantiomerically pure juvenile hormones was assayed by topical application on allatectomizedBombyx fourth instar larvae. JHs tested were (10R)-JH I [methyl (2E,6E,10R,11S)-10,11-epoxy-3,11-dimethyl-7-ethyl-2,6-tridecadienoate], (10S)-JH I [methyl (2E, 6E, 10S, 11R)-10,11-epoxy-3,11-dimethyl-7-ethyl-2,6-tridecadienoate], (10R)-JH III [methyl (2E,6E,10R)-10,11-epoxy-3,7,11-trimethyl-2,6-dodecadienoate] and (10S)-JH III [methyl (2E,6E,10S)-10,11-epoxy-3,7,11-trimethyl-2,6-dodecadienoate]. Among these compounds, natural (10R)-JH I was most active and the dose needed to induce 50% larval molting was 0.04 μg/larva; it was approximately 12,000 times more active than unnatural (10S)-JH I. Though natural (10R)-JH III showed slight biological activity, it was only one three-thousandth of that of (10R)-JH I. Unnatural (10S)-JH III exhibited no biological activity at the levels assayed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02027321
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    An α-fetoprotein producing pancreatic cystadenocarcinoma (1994)
    Springer
    Journal of molecular medicine 72 (1994), S. 377-380 
    Details
    ISSN: 1432-1440
    Keywords: Mucinous cystadenocarcinoma ; Pancreas ; α-Fetoprotein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An autopsy case of an 83-year-old Japanese woman with pancreatic cancer with significantly elevated serum α-fetoprotein levels is reported. The pancreatic tumor was a mucinous cystadeno-carcinoma with multiple metastasis to the liver. The immunohistochemistry for α-fetoprotein revealed positive reactivity in the cytoplasm of cancer cells in the primary and liver metastatic lesions. The current case is the first reported in which mucinous cystadenocarcinoma of the pancreas produced α-fetoprotein.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252831
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