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  • Articles: DFG German National Licenses  (43)
  • 2005-2009  (2)
  • 1985-1989  (41)
  • 21
    Electronic Resource
    Electronic Resource
    Structure of a novel Diels–Alder adduct derived from a thebaine analogue (1987)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 43 (1987), S. 1773-1775 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270187090231
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  • 22
    Electronic Resource
    Electronic Resource
    Structure of 4-tert-butyl-2,6-dimethylacetophenone and comparison with its FeCl3 complex (1987)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 43 (1987), S. 294-296 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270187096070
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    Paper (German National Licenses)
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  • 23
    Electronic Resource
    Electronic Resource
    Structure of a new deoxygenated etorphine analogue (1987)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 43 (1987), S. 2384-2386 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270187087675
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  • 24
    Electronic Resource
    Electronic Resource
    Ratio between large and small carboxy-terminal molecular forms of cholecystokinin in brains of different species (1986)
    Springer
    Cellular and molecular life sciences 42 (1986), S. 1240-1241 
    Details
    ISSN: 1420-9071
    Keywords: Cholecystokinin ; radioimmunoassay ; species difference ; molecular heterogeneity ; brain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ratio between large and small carboxy-terminal forms of cholecystokinin in brain extracts from man, pig, dog, rat, chicken, frog and trout was determined by two sequence-specific radioimmunoassays. It was found that the relative amounts of large forms of cholecystokinin; are higher in mammalian brain than in brains of lower species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01946403
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  • 25
    Electronic Resource
    Electronic Resource
    The influence of different nutrients on plasma cholecystokinin levels in the rat (1988)
    Springer
    Cellular and molecular life sciences 44 (1988), S. 21-23 
    Details
    ISSN: 1420-9071
    Keywords: Rats ; nutrients ; cholecystokinin ; pancreatic secretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Isocaloric and isovolemic amounts of protein (casein), fat (intralipid) and carbohydrate (saccharose) and an isovolemic control solution of water were administered intragastrically to conscious rats. The plasma CCK levels, determined by a sensitive and specific radioimmunoassay, showed an increment of 6.3±0.6, 2.7±0.5, 1.7±0.4 and −0.9±0.4 pM, respectively (basal value 2.5±0.3 pM). The threshold increment of plasma CCK to stimulate pancreatic enzyme secretion by exogenous CCK was found to be 1.5 pM. It is therefore concluded that casein is a potent stimulus for CCK secretion and pancreatic secretion, but that fat and even carbohydrate, although less potent, also produce a CCK increment above the threshold for pancreatic secretion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01960229
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  • 26
    Electronic Resource
    Electronic Resource
    The intraneoplastic chemotherapy in a rat brain tumour model utilizing methotrexate-polymethylmethacrylate-pellets (1987)
    Springer
    Acta neurochirurgica 87 (1987), S. 70-75 
    Details
    ISSN: 0942-0940
    Keywords: Rat brain glioma ; intraneoplastic methotrexate treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In an experimental glioma model, using ethylnitrosourea induced and subsequently intracerebrally implanted tumours in BD-IX rats, the effectiveness of intratumoural application of methotrexate (MTX) by stereotactic implantation of polymethylmethacrylate (PMMA) pellets containing MTX, has been studied. Tumour volume 10 days after pellet implantation as well as survival rates of treated, untreated and control animals have been the criteria of the effect of treatment. Tumour volume was significantly smaller in treated compared to untreated animals. The survival rate of untreated to treated animals increased 150 and 233% respectively when compared with the control animals. Thus a positive therapeutic effect of MTX-PMMA pellet implantation in the experimental glioma could be proven. Possible consequences for the treatment of human gliomas are shortly discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02076020
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  • 27
    Electronic Resource
    Electronic Resource
    Premetamorphic lateritisation in Proterozoic metabasites of Rogaland, SW Norway (1989)
    Springer
    Contributions to mineralogy and petrology 103 (1989), S. 306-316 
    Details
    ISSN: 1432-0967
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Heterogeneous layers of granulite facies metamorphic basites of the Proterozoic supracrustal Faurefjell Formation in Rogaland, S.W. Norway, display an extreme chemical variation. Within a single layer the bulk chemical composition gradually changes from approximately basaltic in basic granulites to alumina-iron-rich in granofelses. Component-ratios and composition-volume relations indicate open-system chemical reactions mainly involving the extraction of silica. Apparent enrichment in Fe, Ti, P, Al, Zr, Ni, Co, Zn, Y, Nb, Hf and REE and variations in resulting metamorphic mineral assemblages are related to premetamorphic progressive lateritisation of a basaltic protolith. The weathering generated a continuous chemical suite from SiO2=48 wt%, Fe2O3=10 wt% and Al2O3=19 wt% in the basic granulites to 14 wt%, 40 wt% and 25 wt% in the Fe-Al granofelses. Metasomatism during diagenesis and during (very) high-grade metamorphism (1200–900 Ma) further perturbed the concentrations of relatively mobile elements Ca, Mg, K, Rb, Sr, Ba, Na and Li in the laterites without affecting the transition metal ratios. In particular, the REE did not fractionate differentially during the supracrustal and metasomatic alteration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00402917
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  • 28
    Electronic Resource
    Electronic Resource
    High integrated fluid rock ratios during metamorphism at Naxos: evidence from carbon isotopes of calcite in schists and fluid inclusions (1989)
    Springer
    Contributions to mineralogy and petrology 103 (1989), S. 123-126 
    Details
    ISSN: 1432-0967
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00371369
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  • 29
    Electronic Resource
    Electronic Resource
    Improvement of cardiac output estimation by the thermodilution method during mechanical ventilation (1986)
    Springer
    Intensive care medicine 12 (1986), S. 71-79 
    Details
    ISSN: 1432-1238
    Keywords: Cardiac output ; Flow modulation ; Mechanical ventilation ; Thermodilution method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The reliability of cardiac output estimation by thermodilution during artificial ventilation was studied in anesthetized pigs at the right side of the heart. The estimates exhibited a cyclic modulation related to the ventilation. The amplitude of the modulation was independent of the level of positive end-expiratory pressure, ventilatory pattern and volemic loading of the animals. However, a non-constant phase relation existed between the ventilatory cycle and the modulation. Single observations at a fixed moment in the ventilatory cycle are therefore not appropriate for estimation of mean cardiac output nor for studying its relative changes. The averaging of estimates spread equally over the ventilatory cycle led to a much larger reduction in the deviation of the averages from the mean cardiac output than an averaging procedure of randomly selected estimates. The accracy of estimation of mean cardiac output by two estimates equally spread in the ventilatory cycle was equal to the accuracy obtained by averaging five randomly selected estimates. Averaging four estimates, equally spread in the cycle, appeared to be the optimal procedure. For 89% of all averages an accuracy of 5% around the mean was obtained and for 99% an accuracy of ±10%.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00254515
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  • 30
    Electronic Resource
    Electronic Resource
    Suppression of spontaneous breathing during high-frequency jet ventilation (1987)
    Springer
    Intensive care medicine 13 (1987), S. 315-322 
    Details
    ISSN: 1432-1238
    Keywords: PEEP ; Lung stretch ; Respiratory drive ; Carbon dioxide ; Piglets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of ventilatory frequency of high-frequency jet ventilation (HFJV) from 1 to 5 Hz, apart from changes in thoracic volume, on spontaneous breathing activity was studied in Yorkshire piglets under pentobarbital anesthesia. The highest PaCO2 at which the animals did not breathe against the ventilator (apnea point) was established either by changing minute volume of ventilation or by adding CO2 to the respiratory gas. The higher the apnea point, the higher the suppression of spontaneous breathing activity was assumed to be. If the apnea point was searched for by changing minute volume a progressive increase of suppression of spontaneous respiratory activity was found at ventilatory rates of 3 Hz or more, concomitantly with a rise in end-expiratory pressure (PEE). In case the tidal volume was kept constant, increase of ventilatory rate resulted in a tremendous increase of lung volume, together with considerably higher levels of PEE. When under these conditions the apnea point was searched for by adding CO2 to the respiratory gas a much higher CO2-drive was needed for spontaneous breathing and therefore a much stronger inhibition of spontaneous breathing was concluded. By placing the animals in a body box in which pressure could be varied, thoracic volume could be kept constant during HFJV. When thoracic volume was kept constant in this way a constant tidal volume at increasing jet frequencies resulted in only a slight increase in suppression of spontaneous breathing. We conclude that the increase in lung volume is a major factor in suppressing central respiratory activity during HFJV. Jet frequency by itself might be an additional suppressive factor. Airway CO2 did not seem to have an important effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00255786
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