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  • Articles: DFG German National Licenses  (13)
  • 2000-2004  (5)
  • 1990-1994  (8)
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  • Articles: DFG German National Licenses  (13)
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  • 1
    Electronic Resource
    Electronic Resource
    Adsorption of benzene on porous amorphous hydrogenated carbon films (1992)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 71 (1992), S. 3806-3811 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The annealing effect on porosity of amorphous hydrogenerated carbon thin films was studied using a quartz crystal microbalance. As-prepared films show a mesoporous structure and a low adsorption capacity which is proportional to film thickness. Porosity of the as-prepared film is estimated at about 0.15. Baking in vacuum changes the film to be highly microporous and significantly increases the porosity of the films to over 0.40, depending annealing history. Outgassing during the annealing process plays an important role in the formation of porosity. Heat treatment first opens micropores in the slightly mesoporous film. Further heating increases the number and size of micropores, and also produces mesopores. With prolonged heating at high temperatures, further outgassing occurs, resulting in collapsing of the films.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.350894
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    One-week omeprazole, furazolidone and amoxicillin rescue therapy after failure of Helicobacter pylori eradication with standard triple therapies (2002)
    Oxford UK : Blackwell Science Ltd.
    Alimentary pharmacology & therapeutics 16 (2002), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To test the efficacy of omeprazole, furazolidone and amoxicillin triple therapy for the treatment of Helicobacter pylori infection after failure of standard first-line therapy recommended by the Asia-Pacific Consensus on the management of H. pylori infection.〈section xml:id="abs1-2"〉〈title type="main"〉Methods:Patients with failed H. pylori eradication received omeprazole, 20 mg, furazolidone, 100 mg, and amoxicillin, 1 g, all twice daily for 1 week. Endoscopy (CLO test, histology and culture) was performed before treatment. Post-treatment H. pylori status was determined by 13C-urea breath test 6 weeks later.〈section xml:id="abs1-3"〉〈title type="main"〉Results:Fifty patients were recruited. Resistance to metronidazole, clarithromycin and both drugs was in the range of 50–64%, 60–75% and 40–50%, respectively, after failure of first-line therapy. Amoxicillin resistance was not found. The intention-to-treat and per protocol H. pylori eradication rates were 52% and 53%, respectively. Patients with double resistance to metronidazole and clarithromycin showed the lowest eradication rate (38%), which was significantly lower than that of patients with sensitive strains (88%). Side-effects were minimal and compliance was excellent (98%).〈section xml:id="abs1-4"〉〈title type="main"〉Conclusions:One-week omeprazole, furazolidone and amoxicillin rescue therapy achieved a high eradication rate in strains sensitive to metronidazole and clarithromycin. This is a cheap and safe rescue regimen when guided by pre-treatment sensitivity testing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2002.01223.x
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  • 3
    Electronic Resource
    Electronic Resource
    Relationship Between Mammographic Breast Density and Tamoxifen in Women with Breast Cancer (2004)
    Oxford, UK : Blackwell Science Inc
    The @breast journal 10 (2004), S. 0 
    Details
    ISSN: 1524-4741
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract:  Previous studies have reported that tamoxifen use is associated with a decrease in mammographic breast density. This is a potentially valuable finding since mammographic sensitivity is limited by breast density. Anything that reduces breast density would theoretically enhance the sensitivity of mammography for the detection of breast cancer in women at an earlier stage when it is more curable. We performed a retrospective study investigating the potential effect of tamoxifen on breast density. The data for this retrospective study were collected from the records of 52 charts from a single medical oncologist. Patients with breast cancer were selected regardless of stage or age at the time of diagnosis or treatment, as long as their charts had records of bilateral mammograms. For each breast on each woman, both mediolateral oblique and craniocaudal views were reviewed independently by two radiologists on two separate occasions to obtain inter- and intraobserver variability. Two methods of classifying breast density were used: the Breast Imaging Reporting and Data System (BI-RADS), and measurements of percent density. Only age and menopausal status were found to be associated with breast density. There was no correlation between breast density and tamoxifen use (past or present). Our study shows no association between tamoxifen use and breast density. We confirm previous observations that breast density is inversely correlated with age and postmenopausal status. 
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1075-122X.2004.21332.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Genetic identification of exported proteins in Streptococcus pneumoniae (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 9 (1993), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: A strategy was developed to mutate and genetically identify exported proteins in Streptococcus pneumoniae. Vectors were created and used to screen pneumococcal DNA in Escherichia coli and S. pneumoniae for translational gene fusions to alkaline phosphatase (PhoA), Twenty five PhoA+ pneumococcal mutants were isolated and the loci from eight of these mutants showed similarity to known exported or membrane-associated proteins. Homologues were found to: (i) protein-dependent peptide permeases, (ii) penicillin-binding proteins, (iii) Cip proteases, (iv) two-component sensor regulators, (v) the phospho-enolpyruvate:carbohydrate phosphotransferase permeases, (vi) membrane-associated dehydrogenases, (vii) P-type (E1E2-type) cation transport ATPases, (viii) ABC transporters responsible for the translocation of the RTX class of bacterial toxins. Unexpectedly one PhoA+ mutant contained a fusion to a member of the DEAD protein family of ATP-dependent RNA helicases suggesting export of these proteins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1993.tb01233.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Periodic painful purpura: Fact or factitious? (2004)
    Oxford, UK : Blackwell Science, Ltd
    Australasian journal of dermatology 45 (2004), S. 0 
    Details
    ISSN: 1440-0960
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 60-year-old woman with multiple psychosocial issues presented with a history of spontaneous painful bruising on her left upper arm. Extensive investigations did not reveal any abnormality apart from an elevated activated partial thromboplastin time as a result of factor XII deficiency. An autoerythrocyte sensitization test reproduced the tender bruises on her back. Our patient reported relief of pain with promethazine injections. She was subsequently referred to the psychiatric team for ongoing assessment and management. Having an awareness of this rare condition will assist in the prevention of unnecessary investigation of such cases and will allow the early referral of patients for appropriate psychological counselling.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-0960.2004.00049.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Quantitative analysis in the characterization and optimization of protein crystal growth (1994)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 50 (1994), S. 572-590 
    Details
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: Protein crystal growth often depends on the combination of many different factors. Some affect protein solubility directly; others may act indirectly by causing conformational changes. Systematic characterization of these factors can be important for generating good crystals. It can also provide useful insight into the biochemical behavior of the protein being crystallized. Here we focus on statistical methods to achieve these two objectives. (1) Characterization of a protein system by analyzing patterns of crystal polymorphism under different levels of biochemical parameters, such as ligands and pH. Tests of the reproducibility of crystal growth experiments indicate that quantitative scales of crystal quality can be statistically significant. Analysis of variance for a replicated, full-factorial design in which four factors were tested at two levels has been used to demonstrate highly significant, biochemically relevant, two-factor interactions strongly implicating pH and ligand-dependent conformational changes. (2) Optimization of crystal growth via response-surface methods. `Minimum predicted variance' designs provide for efficient response-surface experiments aimed at constructing quadratic models in several dimensions. We have used such models to improve crystal size and quality significantly for three forms of Bacillus stearothermophilus tryptophanyl-tRNA synthetase. In one case we can now avoid having to increase the size by repeated seeding, a difficult procedure that also produces unwanted growth of satellite crystals. Graphs of two-dimensional level surfaces reveal a number of ridges, where the same result is obtained for many combinations of the factors usually varied when trying to improve crystals. An important inference is that it may be better to sample simultaneously for the effects of protein concentration and supersaturation. For a system involving only one crystallizing agent, supersaturation can be approximated as the product of protein and precipitant concentrations. Use of this search direction significantly improves the performance of response-surface experiments. Advantages of growing crystals at stationary points of their response surfaces include better crystals and higher reproducibility, since crystal growth at stationary points is insulated from the deleterious effects of experimental fluctuations. This arises because the derivatives of the response are by definition zero with respect to the experimental variables. Quantitative analysis of appropriately designed crystal growth experiments can thus be a powerful way to characterize complex and interacting biochemical dependencies in macromolecular systems and optimize parameters important to the crystallography.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0907444994001228
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Ductility and Brittleness Simulation during Micro Void Evolution Process of Ductile Material Using Rigid Plastic FEM Based on Gurson Type Yield Function (2000)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 177-180 (Apr. 2000), p. 213-218 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/45/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.177-180.213.pdf
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    In-Situ Coagulation Moulding of Ceramic Suspensions (2004)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 264-268 (May 2004), p. 293-296 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/48/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.264-268.293.pdf
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  • 9
    Electronic Resource
    Electronic Resource
    Preparation of rhodium niobate compound by chemical mixing methods: Effect of preparation method on SMSI behavior of RhNbO4/SiO2 catalysts (1991)
    Springer
    Catalysis letters 9 (1991), S. 43-46 
    Details
    ISSN: 1572-879X
    Keywords: Rhodium niobate ; chemical mixing methods ; ethane hydrogenolysis ; SMSI ; metaloxide interaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Rhodium niobate was prepared as a complex oxide supported on silica via tetra-alkyl ammonium and citrate complexation. After calcination at 750 °C, the complex oxide was formed essentially in the monophasic columbite structure as determined by means of XRD. The two silica-supported RhNbO4 catalysts were tested for their activity toward ethane hydrogenolysis, and a large difference in SMSI behavior was observed for the two preparations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00769079
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  • 10
    Electronic Resource
    Electronic Resource
    The oxidation behaviour of carbon fibres (1994)
    Springer
    Journal of materials science 29 (1994), S. 2250-2254 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The oxidation behaviour of carbon fibres has been studied in air at different temperatures from 550 to 860 °C. A linear relationship has been observed between the carbon fibre size and oxidation time. Experimental results show that the oxidation process is in a mixed control zone, i.e. controlled both by diffusion of the gaseous reactant and product within the boundary layer and by the chemical reaction. The activation energy of carbon burn-off is 140±5 kJ mol−1. The uniform nature of the surface oxidation makes it possible to re-size the carbon fibres to smaller diameters.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01154706
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    Paper (German National Licenses)
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