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  • Artikel: DFG Deutsche Nationallizenzen  (15)
  • 1995-1999  (7)
  • 1990-1994  (8)
  • 1
    Digitale Medien
    Digitale Medien
    Versatile millimeter-wave interferometer with two frequencies in the divertor region of JT-60U (1998)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 69 (1998), S. 3181-3185 
    Details
    ISSN: 1089-7623
    Quelle: AIP Digital Archive
    Thema: Physik , Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: A millimeter-wave interferometer having a capability of concomitant electron temperature measurement, based on the electron cyclotron absorption (ECA) technique, has been developed for divertor diagnostics in JT-60U. Three lines of sight, which pass through the X point horizontally, the inboard divertor and the outboard divertor, are chosen. Two transmitter/receiver units with frequencies of 217 and 183 GHz are employed in order to eliminate the spurious vibration effect using a two color scheme. The two independent units are also arranged to enable two sight line measurements without the vibration compensation. Furthermore, these units allow us to apply the simultaneous ECA diagnostic. Due to the complexity of the transmission line inside the tokamak, the insertion loss is as large as 65 dB. However, the interferometer system can be operated with the signal-to-noise (S/N) ratio of about 20 dB due to the low equivalent input noise of −90 dB m. The measurements performed for several types of the JT-60U discharges indicate the feasibility of the system and the rapid reduction of the electron density near the X point at the high confinement mode transition is first demonstrated. © 1998 American Institute of Physics.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.1149081
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  • 2
    Digitale Medien
    Digitale Medien
    MICRO-CRACK GROWTH AND LIFE PREDICTION OF A 1CrMoV STEEL UNDER AXIAL-TORSIONAL LOW CYCLE FATIGUE AT 550°C (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 17 (1994), S. 0 
    Details
    ISSN: 1460-2695
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Maschinenbau
    Notizen: Abstract— Micro-crack behaviour under axial and torsional loading at 550°C was observed by replica techniques. Cracking behaviour and micro-damage observations were correlated using several parameters that are based on equivalent strain parameters. From the observations, micro-cracking of the oxide films at the crack tip in the strain localized regions seems to be a dominant micromechanism of fatigue crack growth. The maximum principal strain has been identified as an important parameter in multiaxial fatigue at high temperature. A good correlation was obtained between the principal strain range and the crack growth rate. Finally, a life prediction method was proposed based on maximum crack length.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1460-2695.1994.tb00215.x
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  • 3
    Digitale Medien
    Digitale Medien
    Mucinous carcinoma of the skin (1995)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 133 (1995), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1995.tb02771.x
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  • 4
    Digitale Medien
    Digitale Medien
    Small-angle X-ray scattering study of lamellar microdomains in a block copolymer (1991)
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 24 (1991), S. 679-684 
    Details
    ISSN: 1600-5767
    Quelle: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Thema: Geologie und Paläontologie , Physik
    Notizen: Lamellar microdomains formed in the solvent-cast films of a poly[styrene-block-(ethylene-alt-propylene)] (SEP) diblock polymer were studied by small-angle X-ray scattering (SAXS). The SAXS profiles, displaying a series of peculiar scattering maxima which cannot be ascribed to the higher-order diffraction maxima from a regular lamellar spacing, were analyzed based on a model of the one-dimensional paracrystal with a preferential orientation. The results suggest that these maxima are due to higher-order scattering maxima from single lamellar microdomains. The maxima suggest that the relative standard deviation for the distribution of the polystyrene lamellar size is much smaller than that of the lamellar spacing, giving rise to a situation in which the oscillation of the particle factor with scattering vector h persists up to high h values while that of the lattice factor damps to unity at low h values. The SAXS result was interpreted as being due to a bending distortion of the polystyrene lamella with a smaller thickness and a narrower thickness distribution than those of the poly(ethylene-alt-propylene) lamella. A study by transmission electron microscopy tends to support this result.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1107/S0021889890012109
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  • 5
    Digitale Medien
    Digitale Medien
    Biological activity of enantiomerically pure forms of insect juvenile hormone I and III inBombyx mori (1990)
    Springer
    Cellular and molecular life sciences 46 (1990), S. 220-221 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Juvenile hormone ; enantiomer ; biological activity ; Bombyx mori ; allatectomy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Biological activity of enantiomerically pure juvenile hormones was assayed by topical application on allatectomizedBombyx fourth instar larvae. JHs tested were (10R)-JH I [methyl (2E,6E,10R,11S)-10,11-epoxy-3,11-dimethyl-7-ethyl-2,6-tridecadienoate], (10S)-JH I [methyl (2E, 6E, 10S, 11R)-10,11-epoxy-3,11-dimethyl-7-ethyl-2,6-tridecadienoate], (10R)-JH III [methyl (2E,6E,10R)-10,11-epoxy-3,7,11-trimethyl-2,6-dodecadienoate] and (10S)-JH III [methyl (2E,6E,10S)-10,11-epoxy-3,7,11-trimethyl-2,6-dodecadienoate]. Among these compounds, natural (10R)-JH I was most active and the dose needed to induce 50% larval molting was 0.04 μg/larva; it was approximately 12,000 times more active than unnatural (10S)-JH I. Though natural (10R)-JH III showed slight biological activity, it was only one three-thousandth of that of (10R)-JH I. Unnatural (10S)-JH III exhibited no biological activity at the levels assayed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02027321
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  • 6
    Digitale Medien
    Digitale Medien
    Bombyxin gene expression in tissues other than brain detected by reverse transcriptionpolymerase chain reaction (RT-PCR) and in situ hybridization (1996)
    Springer
    Cellular and molecular life sciences 52 (1996), S. 882-887 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Insulin ; insulin-like growth factor ; Bombyx mori ; ovary ; neurosecretory peptide ; Oligotex reverse transcription-polymerase chain reaction
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract Bombyxin is a 5 kDa insulin-related peptide produced in four pairs of medial neurosecretory cells in the brain of the silkmothBombyx mori. We demonstrate here the presence of bombyxin mRNA in tissues other than brain: ganglia, epidermis, testis, ovary, fat body, silk gland, Malpighian tubule, midgut, and hindgut of theBombyx fifth instar larvae. Bombyxin mRNA was detected by Oligotex reverse transcription-polymerase chain reaction (RT-PCR), a rapid and simple procedure of reverse transcription-PCR, and in situ hybridization. The Oligotex RT-PCR method effectively eliminated the contaminating DNA in RNA samples and amplified bombyxin mRNA efficiently. In situ hybridization of theBombyx ovary clearly demonstrated the localization of the bombyxin mRNA in the ovariole. The present study is the first demonstration of expression of brain neurosecretory peptide in tissues other than the central nervous system in insects at RNA level.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01938875
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  • 7
    Digitale Medien
    Digitale Medien
    Excitatory amino acidergic pathways and receptors in the basal ganglia (1991)
    Springer
    Amino acids 1 (1991), S. 339-350 
    Details
    ISSN: 1438-2199
    Schlagwort(e): Amino acids ; Glutamate ; Aspartate ; α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid ; Kainate ; N-Methyl-D-asparate ; Striatum ; Pallidum ; Substantia nigra ; Subthalamic nucleus
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The striatum receives the majority of excitatory amino acidergic input to the basal ganglia from neocortical and allocortical sources. The subthalamic nucleus and the substantia nigra also receive excitatory amino acidergic inputs from neocortex. The subthalamic nucleus, which has prominent projections to the pallidum and nigra, is the only known intrinsic excitatory amino acidergic component of the basal ganglia. Possible excitatory amino acidergic inputs reach the basal ganglia from the intralaminar thalamic nuclei and the pedunculo-pontine nucleus. The striatum is richly endowed with all subtypes of excitatory amino acid receptors and these appear to be inhomogeneously distributed within the striatal complex. The non-striatal nuclei contain lesser levels of excitatory amino acid receptors and the relative proportion of these receptors varies between nuclei. The presence of high densities of excitatory amino acid receptors is a phylogenetically conserved feature of the striatum and its non-mammalian homologues. In Huntington's disease, there is substantial depletion ofα-amino-3-hydroxy-5-methylisoxazole-4-propionic acid, N-methyl-D-aspartate, and kainate receptors within the striatum. In Parkinson's disease substantia nigra, there is significant loss of N-methyl-D-aspartate andα-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00814003
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  • 8
    Digitale Medien
    Digitale Medien
    Gastric adenoma — carcinoma sequence with special reference to p53 and Ki-ras gene alterations (1995)
    Springer
    Virchows Archiv 427 (1995), S. 119-124 
    Details
    ISSN: 1432-2307
    Schlagwort(e): p53 ; Ki-ras ; Gastric carcinoma ; Immunohistochemistry ; Polymerase chain reaction-single-strand conformational polymorphism
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract With the aim of detecting the timing of p53 and Ki-ras gene alterations in the gastric adenoma-carcinoma sequence, 19 early gastric adenocarcinomas arising from adenomas were studied. Immunohistochemically, 5 adenocarcinomas were positive for p53; 3 focally and 2 diffusely. The p53 point mutations were detected in a focal area with p53 immunoreactivity in 2 of the 5 p53-positive adenocarcinomas. This indicated that p53 point mutations may play a less crucial part in malignant conversion of adenoma to adenocarcinoma in the stomach than in the colon. No Ki-ras gene mutations at codons 12 and 13 were detected in any lesion. These results suggest that the adenoma-carcinoma sequence in the stomach has a different mechanism from that in the colon.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00196515
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  • 9
    Digitale Medien
    Digitale Medien
    Prothoracic gland synthesis of 3-dehydroecdysone and its hemolymph 3β-reductase mediated conversion to ecdysone in representative insects (1990)
    Springer
    Cellular and molecular life sciences 46 (1990), S. 716-721 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Molting hormone ; 3-dehydroecdysone ; 3-oxoecdysteroid 3β-reductase ; ecdysteroid ; prothoracic glands
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The prothoracic glands of a variety of insects were tested for their ability to synthesize ecdysteroids in vitro. More specifically, they were evaluated for their ability to produce 3-dehydroecdysone and ecdysone using both radioimmunoassay and reverse phase high performance liquid chromatography. Three categories of insect prothoracic glands were noted: a) those producing much more 3-dehydroecdysone than ecdysone; b) glands synthesizing almost equivalent amounts of each of these two ecdysteroids; c) prothoracic glands that yielded more ecdysone than 3-dehydroecdysone. In addition, the 3-oxoecdysteroid 3β-reductase activity of the hemolymph of these insects was evaluated for its ability to convert 3-dehydroecdysone to ecdysone. The lepidopteran species tested yielded the most potent enzyme activity, although activity was demonstrated in members of other orders. These data indicate that the dehydroecdysone-ecdysone axis is not restricted to moths and butterflies.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01939944
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  • 10
    Digitale Medien
    Digitale Medien
    Gene transfer into insect brain and cell-specific expression of bombyxin gene (1999)
    Springer
    Development genes and evolution 209 (1999), S. 447-450 
    Details
    ISSN: 1432-041X
    Schlagwort(e): Key words Bombyxin ; Insulin ; Bombyx mori ; Electroporation ; Cell-specific expression
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract  A transgene reporter consisting of the bombyxin gene promoter and the green fluorescent protein coding region was introduced into intact brains of the silkworm Bombyx mori by in vitro electroporation. After in vitro culture of the brains, the fluorescence derived from the introduced reporter gene was observed in all cases in eight neurosecretory cells that had previously been identified as bombyxin-producing cells (BPCs). Although the fluorescence was not always observed in all cells, it was specific to BPCs, indicating that the reporter was under the control of the bombyxin gene promoter in a BPC-specific manner. Electroporatical introduction of a reporter gene was therefore found to be a suitable method for analyzing cell-specific expression in intact tissues and to be substitute for germ-line transmission of reporters in the transgenic system. Application of this technique enables us to analyze the cell-specific expression of transgene reporters within a few days and treat more than several dozens of the reporters within 1 month, which is difficult to do with the transgenic system.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004270050277
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