ISSN:
1432-0533
Keywords:
Giant axonal neuropathy
;
Intermediate filaments
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary We report on a 5 1/2 year-old boy with chronic progressive polynèuropathy, ataxia, and pyramidal signs. His hair was not curled. Sural nerve biopsy disclosed many axons enlarged by accumulation of 10-nm neurofilaments and a marked variability in the number of myelinated fibers as well as in the amount of axonal enlargements among different fascicles. These findings and the electrophysiological data were consistent with a giant axonal polyneuropathy with a multifocal fiber loss.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00310034
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