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  • Articles: DFG German National Licenses  (3)
  • 1990-1994  (1)
  • 1985-1989  (2)
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  • Articles: DFG German National Licenses  (3)
Material
Years
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    A combination of a particular HLA-DPβ allele and an HLA-DQ heterodimer confers susceptibility to coeliac disease (1989)
    [s.l.] : Nature Publishing Group
    Nature 339 (1989), S. 470-473 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Molecular analysis has revealed the heterogeneity of the DR and DQ serotypes17'18 and, recently, restriction fragment length polymorphism (RFLP) markers associated with coeliac disease have been observed using DP/319, DPa19'20 and DQa21 complementary DNA probes. Recently, we have developed a simple ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/339470a0
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Unchanging clinical picture of coeliac disease presentation in Campania, Italy (1989)
    Springer
    European journal of pediatrics 148 (1989), S. 610-613 
    Details
    ISSN: 1432-1076
    Keywords: Coeliac disease ; Clinical picture ; Epidemiology ; Adolescence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Four hundred and sixty-three new diagnoses of coeliac disease in children were made during 1973 to 1986 in our department. The distribution of new diagnoses per year did not show any decreasing trend in the period 1973 to 1986. No changing trend in breast feeding attitudes was found in the region during the same period. Analysis of the clinical pattern showed a constant distribution of age at diagnosis, onset of first symptoms and nature of symptoms throughout the period studied. These data suggest that coeliac disease is predominantly genetically determined and its expression is modulated by individual and environmental factors. The stability of the observed prevalence of the disease is parallel to the unchanging pattern of breast feeding attitudes in the region.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00441511
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Abnormalities of gastrointestinal motility in children with nonulcer dyspepsia and in children with gastroesophageal reflux disease (1991)
    Springer
    Digestive diseases and sciences 36 (1991), S. 1066-1073 
    Details
    ISSN: 1573-2568
    Keywords: nonulcer dyspepsia ; migrating motor complexes ; bile salt concentration ; gastric emptying
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In 11 children (mean age 44.2 months) with symptoms suggesting upper intestinal dysfunction (nonulcer dyspepsia), in nine children (mean age 27.3 months) with gastroesophageal reflux (GER) disease, and in seven controls (mean age 20.4 months) we investigated fasting [for 3 hr or until two migrating motor complexes (MMC) were observed] and fed (90 min) antroduodenal motility by means of perfused catheter system; furthermore, we measured both gastric emptying of a radiolabeled milk formula and fasting duodenogastric reflux during manometry by assessing bile salt concentration in gastric aspirates. No structural abnormalities of gastrointestinal tract and organic disorders were detected in the patients. In a high proportion of both groups of patients we found manometric abnormalities of interdigestive and fed motor patterns that were not seen in the controls: absence of antral phase III of MMC; significant decrease of antral and/or duodenal motor activity during fasting and/or fed periods; abnormal propagation or configuration of MMC phase III that was signficantly shorter than in controls; bursts of sustained fasting and/or fed phasic duodenal activity, frequently uncoordinated with adjacent gut segments. When compared to controls, the mean intragastric concentration of bile salts during all MMC phases and the mean 1-hr percent gastric activity of the radiolabeled milk were significantly higher in the two groups of patients. We conclude that in a high proportion of children with nonulcer dyspepsia and of children with GER disease, gastrointestinal manometry may reveal significant irregularities of antral and duodenal motility, which are associated with increased duodenogastric reflux and delayed gastric emptying.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01297448
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    Paper (German National Licenses)
    Fulltext
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