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  • Articles: DFG German National Licenses  (5)
  • 1990-1994  (5)
  • Engineering  (2)
  • 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide  (1)
  • ATP  (1)
  • Aligator plate  (1)
Source
  • Articles: DFG German National Licenses  (5)
Material
Years
  • 1990-1994  (5)
Year
Keywords
  • 1
    ISSN: 1434-0879
    Keywords: Chemosensitivity test ; Collagen gel matrix ; 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide ; Human transitional cell carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An organ culture system using collagen gel matrix (CGM) was modified and established successfully as a rapid and convenient method for determination of anti-cancer drug sensitivities. The cell viability of a tumor fragment was measured by the reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) to a colored formazan product, which allowed for quantitative and simple analysis. The sensitivities of KK-47 bladder tumor from nude mice to various anti-cancer drugs tested corresponded closely to those determined in the originial CGM assay system using tritiated thymidine, which has a high clinical correlation. Our modified method can be used as a practical and highly reproducible chemosensitivity test in vitro.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-0879
    Keywords: Hyperosmolarity ; NaCl ; Neutrophil ; Phosphoenol pyruvic acid ; ATP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Hyperosmolority in the urinary tract inhibits the host defense against bacterial infection. NaCl contributes most to osmolority in the renal medulla and urine. Therefore, we studied the effect of hyperosmolar NaCl on neutrophil function. When osmolarity was increased by NaCl, polymorphonuclear leukocytes (PMNL) became defective in phagocytosis, intracellular killing of bacteria, chemotactic activity, and superoxide production. This coincided with a decrease in the intracellular adenosine triphosphate (ATP) content of PMNL. Both the inhibition of superoxide production and the reduction in ATP content did not occur at 4°C. By increasing ATP content, phosphoenol pyruvic acid (PEP) protected against the decrease in superoxide production. These results suggest that leukocyte function is inhibited by high concentrations of NaCl due to the activation of the Na+−K+ pump. PEP, an ATP precursor, can protect PMNL against osmotic stress by raising the intracellular concentration of ATP.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0932
    Keywords: Rachis cervical ; Arthrodèse postérieure ; Instrumentation ; Arthrodèse par plaques ; Plaques “Alligator” ; Instabilité cervicale ; Cervical spine ; Posterior fusion ; Instrumentation ; Posterior fixation ; Plate fixation ; Aligator plate ; Cervical instability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We have designed a new type of clamping plate called the “Alligator plate” for posterior cervical spinal fixation and used it in some cases with cervical instability. Seventeen patients with cervical instability treated by posterior cervical fixation using Alligator plate were clinically evaluated. As a control group, 21 patients treated by a wire fixation method (cerclage) were also evaluated. Clinical results were evaluated radiographically on dynamic flexion-extension lateral radiographs with confirmation of the fusion mass on oblique-view radiographs. The results of Alligator plate fixation were excellent in 15 patients, good in one and poor in one. The results of wire fixation were excellent in 15 patients, good in three, fair in one and poor in two. A safe and simple alternative instrumentation, the Alligator plate has sufficient stability to be useful for treating instability of the lower cervical spine.
    Notes: Résumé Nous avons créé un nouveau type de plaque à machoire appelée plaque “Alligator” destinée à l'arthrodèse postérieure du rachis cervical et nous l'avons appliquée à quelques cas d'unstabilité cervicale. L'évaluation clinique a porté sur 17 cas présentant une instabilité cervicale traitée par arthrodèse postérieure à l'aide de plaques “Alligator”. L'évaluation a aussi porté sur un groupe témoin comportant 21 cas traités par la méthode du cerclage. Les résultats cliniques ont été évalués radiologiquement d'après les clichés dynamiques de profil en flexion-extension, et confirmation de la fusion osseuse sur les radios de profil. Les résultats obtenus dans le groupe traité par les plaques “Alligator” ont été excellents chez 15 patients, bons chez l'un et mauvais chez un autre. Les résultats obtenus avec le cerclage ont été excellents chez 15 patients, bons chez trois, passables chez un et mauvais chez deux. La plaque “Alligator” représente une alternative intéressante en matière d'implants cervicaux; elle est d'une stabilité suffisante et peut se montrer de ce fait utile dans le traitement de l'instabilité du rachis cervical inférieur.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Communications in Numerical Methods in Engineering 10 (1994), S. 237-248 
    ISSN: 1069-8299
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: In the paper we have developed a new formulation for solution of structural-acoustic coupling problems by boundary elements using the multiple reciprocity method. It is assumed that the structure is composed of plate components and is excited by the external or the internal noise source. The efficiency of the proposed formulation becomes especially remarkable if the boundary-value problem is to be solved repeatedly for different values of frequency. The accuracy of the numerical computations has been compared with the analytical solution in a test example.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 36 (1993), S. 1609-1628 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Both the hypersingular and nearly singular integrals, which appear in the hypersingular boundary integralequations and integral representations of the secondary fields, respectively, are regularized by the application of the superposition principle. Two kinds of the non-singular formulations, namely, those with the strongly singular and weakly singular kernels, are presented in this paper. The formulations are given in terms of the relevant boundary quantities and the collocation at element junctions is possible. Two- and three-dimensional problems are analysed simultaneously in a unique way for either internal or external problems of the potential theory and elasticity.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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