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  • Articles: DFG German National Licenses  (7)
  • Key words Adsorption  (2)
  • Macrophage  (2)
  • dosimetry  (2)
  • (−)-noradrenaline  (1)
Source
  • Articles: DFG German National Licenses  (7)
Material
Years
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Development of an automatic image scanner for nuclear track analysis
    Amsterdam : Elsevier
    International Journal of Radiation Applications & Instrumentation. Part D, 19 (1991), S. 247-248 
    Details
    ISSN: 1359-0189
    Keywords: automatic tracks measurements ; dosimetry ; image analysis ; optical microscope ; overlapping tracks
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/1359-0189(91)90184-J
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Characterization of a nuclear track detector response by microtopography observations and image analysis
    Amsterdam : Elsevier
    Nuclear Tracks And Radiation Measurements (1993) 22 (1993), S. 195-196 
    Details
    ISSN: 0969-8078
    Keywords: automatic track measurements ; dosimetry ; image analysis ; microtopography ; three-dimensional profilometry
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0969-8078(93)90045-6
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Activation of a potassium outward current by zymosan and opsonized zymosan in mouse peritoneal macrophages (1994)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 349 (1994), S. 594-601 
    Details
    ISSN: 1432-1912
    Keywords: Macrophage ; Voltage-clamp ; Potassium current ; Zymosan ; Platelet activating factor ; Calcium ionophore A 23187
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of zymosan and human serum opsonized zymosan on membrane currents of adherent mouse peritoneal macrophages which had been cultured for 5 to 20 days were investigated with the whole-cell voltage-clamp technique. Both stimuli activated an outward current. The outward current activation was transient and lasted about 5 min. In solutions with 10 or 50 mmol/l extracellular potassium concentration the activation of an outwardly directed current occurred at test potentials positive to the respective potassium equilibrium potential. This particle-induced current resembled a calciu-mactivated potassium current which could be activated with the calcium ionophore A 23187 and with platelet activating factor. The order of maximal responses (test potential +55 mV, amplitude given as percentage of the respective control) was: 0.1 μmol/l platelet activating factor (222±36%,n=8,P〈0.01) 〉 1 μmol/l A 23187 (190±24%,n=11,P〈0.01) 〉900 μg/ml opsonized zymosan (134±7%,n=22,P〈0.01) 〉900 μg/ml zymosan (116±5%,n = 21,P〈0.01) The lower efficiency of zymosan as compared to opsonized zymosan is explained in part by a lower percentage of responding cells which was 48% for zymosan and 73% for opsonized zymosan. Macrophages which were pretreated with particles showed a greater reactivity to calcium as compared to untreated cells. Elevation of extracellular calcium from 0.9 to 4.5 mmol/l activated the outward current to 145±12% (n = 11,P〈 0.01) after preincubation with opsonized zymosan and to 144±21% (n = 12,P〈 0.01) under the influence of zymosan while in untreated cells current increase by elevation of extracellular calcium was not significant (120±10%,n = 9, n.s.).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01258465
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Activation of membrane outward currents by human low density lipoprotein in mouse peritoneal macrophages (1993)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 348 (1993), S. 207-212 
    Details
    ISSN: 1432-1912
    Keywords: Macrophage ; Voltage-clamp ; Ionic current ; Low density lipoprotein ; Acetylated low density lipoprotein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The aim of the present study was to search for electrophysiological effects of human lipoproteins on membrane currents in mouse peritoneal macrophages which had been cultured for 5 to 20 days. Whole-cell currents were recorded by using a voltage-clamp technique. Low density lipoprotein (LDL, 100 μg/ml) increased a slowly activating nonspecific cation current (iso) in the positive potential range to 244 ± 23% of the reference (test potential + 55 mV, n = 13, P 〈 0.005). Augmentation of current resulted out of a negative shift of the activation curve along the voltage axis (−22 mV) and an increase of maximally available current. Furthermore, LDL increased a rapidly activating outward current (ifo) at test potentials positive to the potassium equilibrium potential. At +55 mV ifo-amplitude increasedto 165 ± 14% ofreference (n = 16, P 〈 0.005). LDL-induced effects on ifo-current could be mimicked by application of the calcium ionophore A 23187 (1 μmol/l) which led to an increase of ifo-current to 161 ± 25% of the reference (test potential + 55 mV, n = 11, P 〈 0.005). Acetylated-LDL (100 μg/ml, 5–15 min) produced no significant effect on the membrane currents under investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00164800
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Hydrophobic layered double hydroxides (LDHs): selective adsorbents for liquid mixtures (1997)
    Springer
    Colloid & polymer science 275 (1997), S. 681-688 
    Details
    ISSN: 1435-1536
    Keywords: Key words Adsorption ; anionic surfactants ; hydrophobic surfaces ; layered double hydroxide ; swelling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  The external and internal surface area of the calcium aluminum double hydroxide [Ca2Al(OH)6] NO3 ⋅ 2H2O were hydrophobized by the anionic surfactants sodium dodecylsulfate and sodium dodecyl-benzene sulfonate. The adsorption behavior towards liquid mixtures (benzene/n-heptane and n-propanol/ toluene) was studied by determining the surface excess adsorption isotherms, the heats of immersion in these liquids, and the basal spacing, i.e. the expansion of the interlayer space. Both hydrophobic layered double hydroxides (LDHs) adsorbed n-hep-tane, benzene, toluene, and n-pro-panol between the layers with considerable increase of the basal spacing. Interlamellar swelling of the hydrophobizised LDHs in n-heptane was fundamentally different to the behavior of hydrophobized 2 : 1 clay minerals (smectites, vermiculites). The surface excess isotherms for benzene/ heptane mixtures were U-shaped and indicate preferential adsorption of benzene. Dodecylbenzene sulfonate double hydroxide preferentially adsorbed propanol from n-propanol/ toluene mixtures but the dodecyl-sulfate derivative adsorbed both compounds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050135
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Multilayer adsorption with variable thickness at solid–liquid interfaces (1997)
    Springer
    Colloid & polymer science 275 (1997), S. 876-882 
    Details
    ISSN: 1435-1536
    Keywords: Key words Adsorption ; multilayers ; binary mixtures ; layer thickness ; surface layer composition ; adsorption capacity ; free enthalpy of adsorption
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  The multilayer adsorption on the solid/liquid interface in binary mixtures was studied by adsorption space filling with constant and variable layer thickness. Adsorption from benzene/n-heptane mixtures was examined on hydrophilic and hydro-phobic surfaces. The free enthalpy of adsorption, Δ21 G=f (x 1), was calculated from the adsorption excess isotherm by integration of the Gibbs equation. Supposing that the free enthalpy is mainly due to adsorption in the first layer, the composition of this layer can be calculated from the Δ21 G=f (x 1) function. It was established that the adsorption layer thickness in benzene/heptane mixtures increases significantly with increasing benzene content. This statement was supported by X-ray diffraction on hydrophobic clay minerals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050160
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Modulation of pacemaker activity in sheep cardiac Purkinje fibers by stimulation of β-adrenoceptor subtypes (1997)
    Springer
    Basic research in cardiology 92 (1997), S. 25-34 
    Details
    ISSN: 1435-1803
    Keywords: Sheep cardiac Purkinje fibers ; action potentials ; automaticity ; β1-β2- ; adrenoceptors-(−) ; isoproterenol ; (−)-noradrenaline ; procaterol ; bisoprolol ; ICI 118,551
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The electrophysiological effects mediated by β1- and β2- in spontaneously active sheep cardiac Purkinje fibers were investigated using the non-selective agonist (−)-isoproterenol (IPN) and the selective agonists (−)-noradrenaline (β1) and procaterol (β2) in the absence and presence of the selective antagonists bisoprolol (β1) and ICI 118,551 (β2). IPN (0.01 μmol/l) increased the spontaneous rate by 54% and the slope of diastolic depolarization by 68% of the respective control values. Further, IPN increased the action potential duration at −20 mV (APD −20 mV) from 96 to 154 ms, reduced the APD −70 mV by 17% and the duration of the diastole by 39% and slightly hyperpolarized the maximum diastolic potential. These effects were partially inhibited by ICI 118,551 (0.03 μmol/l), diminished by bisoprolol (0.1 μmol/l) and almost completely blocked by the combination of both antagonists. Concentration response curves of IPN were influenced by the selective antagonists as follows: ICI 118,551 (0.03 μmol/l) shifted the curves to the right by 0.2–0.4 log units and increased the slope factor. Bisoprolol (0.1 μmol/l) induced a greater shift to the right by 1.1–1.5 log units. Combination of bisoprolol with ICI 118,551 shifted the curves to the right by 1.5–1.7 log units. Noradrenaline (0.3 μmol/l) elicited similar actions as IPN. Bisoprolol (0.1 μmol/l) shifted the concentration response curves of noradrenaline to the right by 1.1–1.9 log units. Actions of procaterol (0.1 μmol/l) were weak, attained only 15–35% of the maximal effects of IPN and could be blocked by ICI 118,551 (0.03 μmol/l). These results show that the increase of pacemaker activity induced by catecholamines in sheep cardiac Purkinje fibers is predominantly mediated by stimulation of β1. However, contribution of β2 mediated effects could be demonstrated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00803754
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