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  • Articles: DFG German National Licenses  (3)
  • Dog  (2)
  • Desire for death  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Successful antidepressant treatment for five terminally ill cancer patients with major depression, suicidal ideation and a desire for death (1999)
    Springer
    Supportive care in cancer 7 (1999), S. 432-436 
    Details
    ISSN: 1433-7339
    Keywords: Key words Suicidal thought ; Desire for death ; Major depression ; Antidepressant ; Terminally ill cancer patients
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  In the debate on euthanasia and physician-assisted suicide, we have to exclude terminally ill patients in whom the desire for death is caused by major depression. However, it is still not clear to what degree major depression can be treated by psychiatric intervention in this setting. We evaluated the effect of antidepressant treatment in terminally ill cancer patients. Six cancer patients with suicidal ideas thought to be due to major depression were treated with tricyclic antidepressants. Three had requested terminal sedation to relieve them from their suffering. The median survival of five of these patients was 4 weeks after diagnosis; one was lost to follow-up. The efficacy of the antidepressant treatment was assessed using the Hamilton Rating Scale for Depression (HRSD). One week after the start of treatment with antidepressants, five of the six patients showed a marked improvement in their mood and showed no further suicidal thoughts or requests for terminal sedation. The average reduction in the HRSD score was 23.4 points (14–38; SD = 9.9). Antidepressant treatment can be effective in alleviating the desire for death due to major depression, even in terminally ill cancer patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005200050305
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    NADPH-diaphorase and nitric oxide synthase in the canine superior cervical ganglion (1995)
    Springer
    Cell & tissue research 279 (1995), S. 629-631 
    Details
    ISSN: 1432-0878
    Keywords: Key words: NADPH-diaphorase ; Nitric oxide synthase ; Superior cervical ganglion ; Dog
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. By means of NADPH-diaphorase (NADPH-d) histochemistry and nitric oxide synthase (NOS) immunohistochemistry, we demonstrate that considerable numbers of NADPH-d-positive neurons are distributed throughout the canine superior cervical ganglion (SCG). These neurons also show NOS immunoreactivity. This finding indicates that NADPH-d histochemistry, a simple and reliable technique, can be used as a reliable marker of NOS activity in the sympathetic innervation of canine head and neck. The present findings suggest that the participation of nitric oxide in the SCG differs greatly between species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004410050322
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    NADPH-diaphorase and nitric oxide synthase in the canine superior cervical ganglion (1995)
    Springer
    Cell & tissue research 279 (1995), S. 629-631 
    Details
    ISSN: 1432-0878
    Keywords: NADPH-diaphorase ; Nitric oxide synthase ; Superior cervical ganglion ; Dog
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract By means of NADPH-diaphorase (NADPH-d) histochemistry and nitric oxide synthase (NOS) immunohistochemistry, we demonstrate that considerable numbers of NADPH-d-positive neurons are distributed throughout the canine superior cervical ganglion (SCG). These neurons also show NOS immunoreactivity. This finding indicates that NADPH-d histochemistry, a simple and reliable technique, can be used as a reliable marker of NOS activity in the sympathetic innervation of canine head and neck. The present findings suggest that the participation of nitric oxide in the SCG differs greatly between species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00318175
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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