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  • Articles: DFG German National Licenses  (9)
  • Engineering General  (3)
  • FMRFamide  (3)
  • Insulin  (3)
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  • Articles: DFG German National Licenses  (9)
Material
Years
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Receptor-binding kinetics of A-14 and A-19 ^1^2^5I-labelled insulin
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/General Subjects 798 (1984), S. 313-316 
    Details
    ISSN: 0304-4165
    Keywords: Insulin ; Iodination ; Receptor-binding kinetics
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0304-4165(84)90104-1
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A new potentiator of insulin action - Post-receptor activation in vitro
    Amsterdam : Elsevier
    FEBS Letters 163 (1983), S. 50-53 
    Details
    ISSN: 0014-5793
    Keywords: Diabetes ; Insulin ; Insulin resistance ; Obesity ; Receptor
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(83)81160-0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Synergistic stimulatory effect of glucocorticoid, EGF and insulin on the synthesis of ribosomal RNA and phosphorylation of nucleolin in primary cultured rat hepatocytes
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Molecular Cell Research 1092 (1991), S. 367-375 
    Details
    ISSN: 0167-4889
    Keywords: EGF ; Glucocorticoid ; Insulin ; Nucleolin ; Primary cultured hepatocyte ; rRNA
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0167-4889(97)90014-8
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Innervation and control of the heart of a gastropod,Rapana (1987)
    Springer
    Cellular and molecular life sciences 43 (1987), S. 981-986 
    Details
    ISSN: 1420-9071
    Keywords: Molluscan heart ; neurotransmitter ; serotonin ; FMRFamide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The innervation and control of the heart of a prosobranch mollusc,Rapana thomasiana, were studied. Acetylcholine was found to be an inhibitory neurotransmitter. Both serotonin and FMRFamide (Phe-Met-Arg-Phe-NH2) showed excitatory effects on the heart; FMRFamide had greater inotropic and more regulatory chronotropic effects than serotonin. The effects of serotonin were blocked by methysergide, while the effects of FMRFamide and of stimulating the excitatory cardiac nerves were not blocked. Stimulation of circumesophageal ganglia elicited a slow enhancement of heart beat together with body movement. This enhancement was blocked by methysergide. Serotonin was considered to act at the heart as a local neurohormone. Although the mechanism of action of FMRFamide is still not yet clarified, it is possible that FMRFamide plays a physiological role as a cardioregulatory substance, as indicated by the physiological and histological findings.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01952213
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Action and immunoreactivity of neuropeptides in the buccal neuromuscular system of a prosobranch mollusc, Rapana thomasiana (1991)
    Springer
    Cell & tissue research 264 (1991), S. 57-62 
    Details
    ISSN: 1432-0878
    Keywords: FMRFamide ; Catch-relaxing peptide (CARP) ; Radula muscle ; Immunohistochemistry ; Rapana thomasiana (Mollusca)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In a prosobranch mollusc, Rapana thomasiana, the catch-relaxing peptide H-Ala-Met-Pro-Met-Leu-Arg-Leu-NH2 (CARP) was found to depress the contraction of the radula protractor and retractor elicited by electrical stimulations. The action of CARP was in contrast to that of other neuropeptides, H-Phe-Met-Arg-Phe-NH2 (FMRFamide) and H-Phe-Leu-Arg-Phe-NH2 (FLRFamide), which enhanced the contraction of the radula protractor and retractor, respectively. By immunohistochemical examinations, FMRFamide-like immunoreactive neurons were found on the rostral side of the right buccal ganglion and the caudal side of the left ganglion, where some CARP-like immunoreactive neurons were also distributed, indicating a possible coexistence of FMRFamide and CARP. FMRFamide- and CARP-like immunoreactivities were also detected in the neuropile of buccal ganglia, radula nerves arising from the ganglia, and nerve fibers in the radula muscles. The present results suggest that FMRFamide- and CARP-like peptides are involved in the regulation of the contraction of the radula muscles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00305722
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Neuropeptides regulate the cardiac activity of a prosobranch mollusc, Rapana thomasiana (1992)
    Springer
    Cell & tissue research 269 (1992), S. 241-247 
    Details
    ISSN: 1432-0878
    Keywords: FMRFamide ; Catch-relaxing peptide (CARP) ; Heart beat ; Immunohistochemistry-Rapana thomasiana (Mollusca)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Involvement of neuropeptides in the regulation of cardiac activity in a prosobranch mollusc, Rapana thomasiana, was studied physiologically as well as immunohistochemically. A catch-relaxing peptide (CARP) showed strong inhibitory effects on the heart with a lower threshold than acetylcholine. The action of CARP was in contrast to that of another neuropeptide, FMRFamide, which has previously been shown to enhance the heart beat. Benzoquinonium blocked the effects of acetylcholine and stimulation of right cardiac nerves 1 and 3b, but not those of CARP, suggesting that the effects of nerve stimulation are mainly due to the release of acetylcholine. Immunohistochemical examinations demonstrated that FMRFamide-like and CARP-like immunoreactive neurons are distributed in the visceral ganglia. Although a neuron appeared to show weak immunoreactivity to both antisera, evidence for the coexistence of peptides in a single neuron was not exhibited. Positive immunoreactivity to FMRFamide and CARP antisera also appeared in right cardiac nerves 1 and 3. In the heart, FMRFamide- and CARP-like immunoreactive fibers were restricted to the atrium and the aortic end of the ventricle, consistent with the morphological observation of innervation. The present results suggest that FMRFamide- and CARP-like peptides are involved in regulating the heart beat.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319615
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    A comparison of second order convection discretization schemes for incompressible fluid flow (1996)
    Chichester : Wiley-Blackwell
    Communications in Numerical Methods in Engineering 12 (1996), S. 395-411 
    Details
    ISSN: 1069-8299
    Keywords: finite volume ; high-order discretization ; non-oscillatory schemes ; pressure interpolation ; non-staggered grid ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The paper addresses the problem of convection discretization by extension and application of numerical schemes used in compressible flows: SONIC-A, SONIC-B, UNO2, MUSCL and MINMOD to predict steady incompressible recirculating convection dominated flows. A new scheme, SONIC-Q, is proposed together with a third-order non-oscillatory practice for pressure interpolation in non-staggered grids. Finite-volume calculations of the Navier-Stokes equations of a standard 2D driven square cavity standard test case and the laminar flow over a fence using primitive variables and non-staggered grid systems have shown that the schemes are alternatives to the conventional ones used in general algorithms for incompressible recirculating flows. In general these composite high-order schemes have proved to be good candidates to overcome the problems of false-diffusion and unboundedness encountered in non-composite high-order upwind schemes used in incompressible flows.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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    Paper (German National Licenses)
  • 8
    Electronic Resource
    Electronic Resource
    Numerical comparison of momentum interpolation methods and pressure - velocity algorithms using non-staggered grids (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Communications in Applied Numerical Methods 7 (1991), S. 173-186 
    Details
    ISSN: 0748-8025
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Finite-volume calculations of laminar separated flow around a fence are presented using a non-staggered grid system. Using the pressure-weighted interpolation method (PWIM), the role of the under-relaxation factor in this method has been studied. The performance of two pressure-velocity coupling algorithms, viz. SIMPLE and PISO, have been compared as well as the solution fields obtained using non-staggered and staggered grids. A detailed study has been conducted to investigate the occurrence of physically unrealistic convective velocities in the solution fields.The numerical results show that solutions obtained using non-staggered grids are as accurate as those obtained using staggered grids. The presence of very small under/overshoots in the estimated convective fluxes is related to the simultaneous presence of high Péclét numbers and rapidly varying pressure gradients. However, for the complex separated flow investigated, no induced errors were detected in the solution field.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cnm.1630070302
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Comparison of several open boundary numerical treatments for laminar recirculating flows (1993)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 16 (1993), S. 403-419 
    Details
    ISSN: 0271-2091
    Keywords: Outflow boundary conditions ; Laminar recirculating flows ; Non-staggered grid systems ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Several open boundary conditions (OBCs) are compared and evaluated in the framework of the SIMPLE algorithm using staggered and non-staggered grid systems. The benchmark laminar flow test cases used for the OBC evaluation are Poiseuille-Benard flow in a channel and stratified backward-facing step flow. The investigated OBCs are linear explicit step space extrapolation, Orlanski's monochromatic wave, and pressure extrapolation. Orlanski's and pressure extrapolation open boundary treatment for unsteady and steady flows, respectively, yield little reflection and has proved to be adequate for engineering calculations.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650160505
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    Paper (German National Licenses)
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