Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Articles: DFG German National Licenses  (19)
  • 1
    Electronic Resource
    Electronic Resource
    Electrophoretic Polymorphism of Human C4 is Due to Charge Differences in the α-Chain, Presumably in the C4d Fragment (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 14 (1981), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Various common C4 gene products were isolated from serum by immunoprecipitation. After reduction the C4 α-, β-, and γ-polypeptide chains were studied by two-dimensional electrophoresis. Isoelectrofocusing was performed in the first dimension and sodium dodecyl sulphate polyacrylamide gradient gel electrophoresis in the second. The charge differences behind the electrophoretic C4 polymorphism were shown to reside in the 95,000-u(atmic mass units) α-chain. Charge variation closely mirroring the α-chain differences were also found in a 49,000-u fragment of the α-chain, most probably C4d. The basic β-chain could not be studied in detail, but no differences were observed with regard to molecular weight or charge of the γ-chains of the different C4 gene products.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3083.1981.tb00568.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    C4 HAPLOTYPE PRODUCTS AND PARTIAL INHIBITION OF ANTI-RODGERS SERA (1981)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 8 (1981), S. 0 
    Details
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Electrophoretic and serologic investigations of C4 in serum samples from a family material, showed that a weak, or partial, inhibition of anti-Rg sera, was an inherited property of some of the C4 haplotype products. The weak Rg activity was strongly, but not absolutely associated with the C4 FI and C4 I haplotypes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-313X.1981.tb00957.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    ASSOCIATION BETWEEN THE ELECTROPHORETICALLY-DETERMINED C4M HAPLOTYPE PRODUCT AND PARTIAL INHIBITION OF ANTI-Cha (1980)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 7 (1980), S. 0 
    Details
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: C4-coated Ch(a+) red blood cells (RBC) were used as indicator cells in a serum inhibition reaction of anti-Cha, for the determination of the Ch group of serum. This serological study, combined with electrophoretic studies of C4 in a family material, showed that the C4M haplotype product was associated with partial inhibition of anti-Cha.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-313X.1980.tb00723.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Very close linkage between HLA-B and Bf inferred from allelic association (1977)
    [s.l.] : Nature Publishing Group
    Nature 268 (1977), S. 527-528 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1 A 'family tree' of the populations studied. Dimensions are time in generations (in brackets) and assumed numbers of ancestral B8 loci (minimum plausible estimates). Iceland was settled in AD 874 by Norsemen with Irish slaves and had a population of over 70,000 by AD 1100; the Nordic and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/268527a0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Probable linkage of LCAT locus in man to the α haptoglobin locus on chromosome 16 (1974)
    [s.l.] : Nature Publishing Group
    Nature 249 (1974), S. 550-551 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Clinically the disease is characterised by proteinuria, cor-neal opacities and normochromic anaemia with decreased erythrocyte life span. The plasma cholesteryl ester and lyso-lecithin concentrations are decreased, and free cholesterol and lecithin usually increased. Studies of the LCAT-deficient ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/249550a0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    In vivo activation of C3 revealed by crossed immunoelectrophoresis as a parameter of immunological activity in disease
    Amsterdam : Elsevier
    Clinica Chimica Acta 62 (1975), S. 35-41 
    Details
    ISSN: 0009-8981
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0009-8981(75)90277-6
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Identification in blood stains through DNA typing with C4 and HLA-DR probes (1987)
    Springer
    International journal of legal medicine 99 (1987), S. 55-64 
    Details
    ISSN: 1437-1596
    Keywords: DNA-typing ; Complement component C4 ; HLA-DR ; Blood stain identification ; DNA-Typisierung ; Komplement-Komponente C4 ; HLA-DR ; Blutspuren, Identifizierung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Es wird die Analyse des Polymorphismus der Länge eines Restriktionsfragments (RFLP, restriction fragment length polymorphism) beschrieben, wobei eine zweifache Spaltung von DNA-Präparaten mit XbaI und BglII Restriktionsenzymen und Hybridisierung mit C4 und HLA-DR angewandt wird. Bei der gewählten Untersuchungstechnik lassen sich zahlreiche individuelle Variationen in den C4 und DR Genregionen nachweisen. In einem Untersuchungsgut von 46 nicht verwandten Personen wurden in beiden Systemen 37 verschiedene Phänotypen-Muster gefunden, wobei die vorläufigen Werte des Diskriminations-Indexes mit 0.865 für C4 und mit 0.914 für DRβ berechnet wurden. Die Wahrscheinlichkeit einer Übereinstimmung bei Anwendung beider Systeme dürfte etwa bei 1.5 × 10−2 liegen. Die Brauchbarkeit dieser Methode zur Identifizierung individueller Blutspuren wurde anhand der DNA demonstriert, die aus 6 Monate alten, getrockneten Blutspuren von sieben Personen des Untersuchungskollektivs gewonnen wurde. Alle Proben konnten durch Vergleich der DNA-Muster mit denen der zuvor erstellten den entsprechenden Personen eindeutig zugeordnet werden. Es zeigten sich im DNA-Muster der Blutspuren keine u. U. lagerungsbedingte Veränderungen. Aus dieser unter Laborbedingungen durchgeführten D4 und DRβ DNA-Untersuchung kann geschlossen werden, daβ die DNA-Hybridisierungstechnik zukünftig als wichtiges Hilfsmittel bei der Spurenanalyse eingesetzt werden kann.
    Notes: Summary A restriction fragment length polymorphism analysis using double digestion of DNA preparations with XbaI and BglII restriction enzymes and hybridization with C4 and HLA-DR probes is described. The typing conditions selected reveal extensive individual variation in both C4 and DR gene regions. In our panel of 46 unrelated individuals, 37 different phenotypic patterns were recognized when both probes were used, and preliminary discriminative power values of 0.865 and 0.914 were calculated for C4 and DRβ, respectively. The probability of a chance match using both systems is probably about 1.5 · 10−2. The potential of this method for individual identification of blood stains was demonstrated on DNA prepared from 6-month-old dried blood stains from seven panel individuals. The seven individuals were all identified when comparing stain DNA patterns with panel control patterns. No RFLP pattern changes were observed following storage of blood stains. Based on these experiments with C4 and DRβ DNA typing under laboratory conditions, it is concluded that DNA typing with such probes may become a powerful tool in future stain identification analyses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00200369
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    ESD polymorphism in Norway (1976)
    Springer
    Human genetics 〈Berlin〉 34 (1976), S. 63-64 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary ESD phenotype distribution and allele frequencies in 217 Norwegians and 196 Norwegian Lapps are presented. There is good accordance with Hardy-Weinberg distribution, ESD 1 allele frequencies are 0.887 in the Norwegians and 0.872 in the Lapps.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00284436
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Nonlinkage between C6 and chromosome 6 markers (1977)
    Springer
    Human genetics 〈Berlin〉 37 (1977), S. 125-129 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary C6 typing was performed in a family material by two different techniques: serum or plasma samples were subjected either to high-voltage agarose gel electrophoresis or to isoelectric focusing in polyacrylamide gel slabs. Proteins with C6 activity were then visualized by a specific, hemolytic assay. In 81 unrelated adults within the family material the following allele frequencies were found: C6 A:0.61 and C6 B:0.39. Linkage studies exclude linkage between C6 and HLA region marker loci, and also between C6 and another chromosome 6 marker locus PGM3.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00393574
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Genetic linkage relations of the sixth component of complement (C6) (1979)
    Springer
    Human genetics 〈Berlin〉 46 (1979), S. 181-192 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Linkage relations between the C6 and 33 other genetic marker loci have been analyzed in Norwegian pedigrees, including 114 matings with 388 informative children, by use of the MOSM computer program. No suggestion of linkage was found. Very close or close linkage (θ〈0.06) has been ruled out for males between C6 and the following 19 marker loci: GPT, HLA+Bf, Rh, C3, Hp, PGM 3, Km, Gm, Fy, Gc, AB0, Jk, GLO 1, K, MNSs, PTC, ACP 1, PGM 1 and Pi. For several of the relations even loose linkage is unlikely.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00291920
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...