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  • Electronic Resource  (8)
  • 1980-1984  (8)
  • 1950-1954
  • 1983  (8)
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 10 (1983), S. 0 
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The ability of verapamil to induce a contractile response in skeletal muscle was investigated using the canine isolated, blood-perfused diaphragm preparation.2. Verapamil-induced contracture was characterized by a biphasic increase in muscle tension consisting of an initial phasic and subsequent tonic contracture.3. The second tonic component of the verapamil-induced contracture was inhibited by procaine, but procaine had no effect on the initial phasic contracture.4. Verapamil potentiated both KCl- and caffeine-induced contractures during the second tonic stage. This action might be explained by enhancement by the drug of availability, or by an increased sensitivity of the contractile machinery to calcium liberated by membrane depolarization or by the calcium-induced calcium release mechanism.5. The second tonic component of verapamil-induced contracture was much less than the initial phasic component. It seems, therefore, that the calcium release induced by the procaine-resistant process is the principal action of verapamil in inducing contracture in skeletal muscle.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 39 (1983), S. 1370-1373 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A low molecular weight cadmium- and copper-binding protein, induced in the liver of the frog,Xenopus laevis, by the administration of cadmium, was shown to consist of a single isoprotein and was characterized as an amphibian metallothionein based on its high cysteine and metal content, its low molecular weight, and the lack of aromatic amino acids.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 59 (1983), S. 159-166 
    ISSN: 1432-0533
    Keywords: Twitcher mouse ; Oligodendroglia ; Cellular degeneration ; Myelin sheaths ; Globoid cell leukodystrophy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Morphological alterations of oligodendroglia were investigated in the spinal cord of the twitcher mouse, an authentic murine model of human globoid cell leukodystrophy (GLD) from day 5 to day 45 postnatal (p.n.). Typical inclusions were seen in the perikarya as well as the processes of oligodendroglia after day 10 with increasing frequency. The majority of the inclusions was non-crystalloid but rather needle-like or slender tubular in appearance. Ultrastructural features of cellular degeneration became first noticeable on days 25–30 in the oligodendroglial cytoplasm. These consisted of an increased number of microtubules and/or smooth cisterns, dispersed ribosomes, alteration of endoplasmic reticulum forming stacked lamellae or whorles, vesiculation or vacuolation of cytoplasm. The number of degenerating oligodendroglia increased in the older twitcher mice, so did the degenerating myelin sheath. However, even on day 45, when globoid cells became conspicuous in subpial and perivascular regions, many oligodendroglia and myelin sheaths were still well preserved. These observations suggested that oligodendrogial degeneration resulted in the degeneration of myelin sheaths but globoid cells appeared even before morphological evidence of myelin degeneration, presumably in response to the biochemical alterations resulted from the deficiency of galactosylceramidase.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 59 (1983), S. 316-318 
    ISSN: 1432-0533
    Keywords: Intracytoplasmic inclusions ; Thalamus ; Young mice ; Neurofilament
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neuronal intracytoplasmic inclusions were found in the ventrolateral and posterior nuclei of the thalamus of 3-month-old thiamine-deficient mice and quaking mice. An electron-microscopic study revealed that these inclusions were composed of condensation of parallel rectilinear 10-nm filaments with interconnecting cross-bridges as a hallmark of neurofilaments. They were morphologically indistinguishable from those described in aged mice. This observation indicates that neuronal inclusions in the thalamus, which have been constantly reported in aging mice, can be seen even in young mice in the presence of cellular metabolic disturbances.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 2 (1983), S. 805-807 
    ISSN: 1573-4811
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 104 (1983), S. 341-347 
    ISSN: 1573-5117
    Keywords: rotifers ; occurrences ; pools ; lake ; intentional ; change
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A comparison of population dynamics of rotifers under natural conditions with those under intentionally-changed ones was carried out at one Lake and five outdoor pools. In Lake Numasawa, dominant rotifers under natural conditions for the past two years were Polyarthra trigla vulgaris, Kellicottia longispina, Ploesoma truncatum, Asplanchna priodonta and Filinia longiseta. Keratella hiemalis, K. cochlearis, K. valga tropica, Brachionus caudatus and Ascomorpha saltans appeared sporadically. Three months after the start of circulation of part of the lake water by a water power plant no remarkable changes were observed as far as the seasonal and vertical distribution of dominant rotifers are concerned. In five pools with different kinds and ratios of covering by such macrophytes as Eichornia and Lemna or reed screen, three types of rotifer communities were found. Type I: Liliferotrocha sp., Brachionus calyciflorus, (B. budapestinensis), B. angularis, K. valga tropica, etc., in which both densities and frequencies were generally reduced in proportion to the ratio of covering either with macrophytes or reed screens. Type II: Filinia longiseta, Polyarthra trigla vulgaris, Asplanchnella sieboldi, etc. in which densities and frequencies were increased by covering either with macrophytes or reed screens. Type III: Trichocerca pusilla, B. quadridentatus, B. leydigi rotundus, Scaridium longicaudum, Euchlanis dilatata, Dicranophorus sp., etc, in which no precise correlation was found between occurrences of the Rotifers and ratio of covering.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 21 (1983), S. 3181-3189 
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Colorless, transparent, and filmy polymers prepared from mixtures of tetramethylsilane (TMS) and ammonia gas (NH3) were investigated by elemental analysis, infrared (IR) spectroscopy, and ESCA. These polymers contained a large amount of nitrogen residues in the form of amine, amide, and amine oxide groups. Their concentration varied with the composition of the starting TMS/NH3 mixtures. The mixing of NH3 gas with TMS influenced the chemical state of Si residues and accelerated the oxidation of Si atoms to form silicon oxides such as SiO, Si2O3, and SiO2. The polymers formed by glow discharge polymerization in the TMS/NH3 mixtures were combinations of Si- and N-containing polymers and silicon oxides.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Letters Edition 21 (1983), S. 353-357 
    ISSN: 0360-6384
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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