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  • Electronic Resource  (24)
  • 2005-2009  (2)
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  • Electronic Resource  (24)
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  • 2005-2009  (2)
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  • 1
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Mice were injected for 1–2 months daily with 10 mg immunoglobulin G (IgG) from four patients with Lambert-Eaton myasthenic syndrome (LEMS); control mice were injected with pooled human IgG from normal donors. Gastrocnemius muscles were homogenised for the assay of acetylcholine (ACh), choline acetyltrans-ferase (ChAT), and cholinesterase (ChE). The ACh, ChAT, and ChE contents of gastrocnemius muscles from “LEMS mice” were about the same as the control values, which were 180 pmol, 40 nmol * h−1 (37°C), and 15 μmol * h−1 (37°C), respectively. Hemidiaphragms were treated with an irreversible ChE inhibitor (Soman) and incubated at 20°C for estimation of ACh release. Resting ACh release from experimental muscles was reduced by about 25% (P2 〈 0.05) and the release evoked by 3 s−1 nervous stimulation by 50% (P2 〈 0.05). On the other hand, 50 mM KCl-induced transmitter release was not abnormal in LEMS mice. The findings indicate that IgG antibody from patients with LEMS may bind to nerve terminal determinants that are involved in quantal and nonquantal ACh release.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 76 (1994), S. 4511-4515 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: An experiment was performed in order to determine whether a first-order or second-order mechanism governs the re-emission of deuterium molecules from graphite during D+ bombardment. The order of the release mechanism should be reflected in the dependence of the re-emission on the incident flux density. No flux density dependence was observed, indicating a first-order process, in agreement with a hydrogen transport model where the rate of molecule release is determined by a first-order process involving H diffusion within graphite crystallites.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 64 (1994), S. 3476-3478 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Using high-resolution transmission electron microscopy (HRTEM), we have studied InAs/GaSb superlattices grown by molecular beam epitaxy. Our HRTEM observations indicate that the apparent interface width is on the order of 1 monolayer for InSb-like interfaces, and on the order of 2 monolayers for GaAs-like interfaces. The combination of these results with x-ray diffraction and Raman scattering measurements leads us to conclude that these interface widths are principally due to roughness rather than to interfacial diffusion.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK; Malden, USA : Blackwell Science Inc
    Ground water 43 (2005), S. 0 
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 32 (1994), S. 0 
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: Measurements of air-permeability in outcrops provide a means of obtaining numerous spatially distributed measurements for statistical analysis and subsequent parameterization of ground-water flow and transport modeling. The air-minipermeameters previously used for such studies generally consist of a compressed air source, rotameters, and diaphragm gauges. We present a lightweight syringe-based air-minipermeameter (LSAMP) design that is significantly more portable than previous instruments. The prototype model is contained in a 12.7 × 15.2 × 23 centimeter (5 × 6 × 9 inch) electrical box and weighs approximately 2 kilograms. The prototype LSAMP has a sampling range of 0.5 to 200 darcys. Individual measurements in this range require less than one minute. Permeability measured with the LSAMP closely correspond to permeability measured with a traditional minipermeameter and those measured on cores. Measurement error caused by soil moisture is less than 5 percent for volumetric water contents less than 5 percent. An analysis of variance on 38 triplicate measurements indicates that the variability associated with measurement error is much less than the range of measured values. Repeated permeability measurements under field conditions on two standard cores indicate that while the measurement error is greater under field conditions, the prototype device field performance is consistent with laboratory calibration results.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Microbiology 38 (1984), S. 315-338 
    ISSN: 0066-4227
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 30 (1994), S. 0 
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Digestive enzymes in faeces have been reported to posses skin irritation potential. The present study was designed to investigate the in vivo irritant potentials of faecal concentrations of proteolytic and lipolytic digestive enzymes in bile salt mixtures. In a 21-day cumulative irritation assay, clinical evaluation and noninvasive bioengineering techniques were used. 5 days occlusive exposure to phosphate buffer (pH = 8) caused no visual skin damage but reflectance spectroscopy demonstrated significant vasodilation (p 〈 0.01) and increases in transepidermal water loss (TEWL) and skin pH were also observed (p 〈 0.01). These increases were still present at days 12 and 19. Occlusive exposure to physiologic concentrations of faecal enzymes resulted in significant visual and objective scores at day 5, 12, and 19, with increased readings as a function of exposure time (p 〈 0.01). The enzyme mixture containing lipase caused delayed onset of skin erythema and epidermal barrier disruption compared to elastase and chymotrypsin containing solutions. Prolonged occlusive exposure to digestive enzymes in faecal concentrations caused severe skin erythema and epidermal barrier disruption in a human model, suggesting a possible etiologic role of digestive enzymes in perianal, circumstomal or diaper dermatitis.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. Extracts of the tunicate Ecteinascidia turbinate were used in preventing Aeromono hydrophila infection in the American eel, Anguilla rostrata. Intraperitoneal injection of the extract 2 days after bacterial challenge was shown to increase dramatically eel phagocytic activity and resistance to disease. Intravenous injection of the extract 2 days post-bacterial injection was shown to increase antibody titres. This study helps to substantiate the possible use of E. turbinata extract in treating eel diseases. The exact nature of its protective effect will be dependent on the time and route of its delivery.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 22 (2005), S. 0 
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  Obesity is a risk factor for adenocarcinomas of the oesophagus and gastric cardia. Diabetes mellitus might mediate that association.Aim:  To estimate the risk of diabetes mellitus on the development of adenocarcinoma of distal oesophagus and gastric cardia beyond that of gastro-oesophageal reflux disease.Methods:  A case–control study was performed using a national administrative database of the Veterans Administration.Results:  A total of 311 cases of cancer and 10 154 controls were identified. Gender, age, and race were risks for cancer. Diabetes was diagnosed in 36% of cases, and 32% of controls (P = 0.15). Diabetic complications were diagnosed in 14% of cases and 13% of controls (P = 0.60). Multiple logistic regression confirmed the absence of an association between cancer and diabetes (odds ratio 1.1, 95% confidence interval 0.8–1.5) or diabetic complications (odds ratio 0.8, 95% confidence interval 0.6–1.3), adjusting for age, gender, and race.Conclusions:  Within the limitations of this case–control study, there is no evidence of an association between diabetes and adenocarcinoma of the oesophagus or gastric cardia among US veterans with gastro-oesophageal reflux disease.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 50 (1994), S. 208-216 
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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