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  • Electronic Resource  (2)
  • 1985-1989  (2)
  • 1985  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 328 (1985), S. 351-353 
    ISSN: 1432-1912
    Keywords: Bay K 8644 ; Insulin secretion ; Mouse pancreatic islets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of the dihydropyridine derivative Bay K 8644 upon insulin secretion by perifused isolated mouse pancreatic islets were examined. At a non-stimulatory glucose concentration (5 mmol/l) Bay K 8644 (1 μmol/l) did not stimulate insulin release. However, the same drug concentration enhanced the insulin secretory responses to an intermediate (15 mmol/l) or high (30 mmol/l) glucose concentration by 80 or 90%, respectively. Bay K 8644 was half maximally effective at 0.1 μmol/l and maximally effective at 1 μmol/l. The results are compatible with the view that voltage-dependent calcium channels are essential for stimulus-secretion coupling in pancreatic B-cells.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 366 (1985), S. 702-702 
    ISSN: 1435-2451
    Keywords: Dupuytren's contracture ; Prophylactic surgery ; Reconstructive surgery ; Documentation ; M. Dupuytren ; Vorsorglicher Eingriff ; Rekonstruktiver Eingriff ; Dokumentation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der M. Dupuytren ist eine chronisch progrediente Fibromatose der Palmaraponeurose und der Digitalfascien unbekannter Genese mit einer Morbidität von 1–3%. Der beste Zeitpunkt für die Operation ist gegeben, wenn die Summe der Streckdefizite an einem Finger 20–30° nicht überschreitet. Die Methode der Wahl ist die komplette Entfernung der Palmaraponeurose und der erkrankten Digitalfascien. Bei fortgeschrittenen Kontrakturen an den Fingern sind evtl. Z-Plastiken, freie Hauttransplantationen and Eingriffe an Bändern and Gelenkkapseln erforderlich. Ein Modell der Dokumentation zur Qualitätssicherung wird vorgestellt.
    Notes: Summary Dupuytren's contracture is a chronic and progressive fibromatosis of the palmar aponeurosis and digital fascia. Morbidity is about 1%-3% and the cause is not yet known. The best time for prophylactic surgery is when the degree of deformity has reached a finger flexion of 20°–30°. Complete fasciectomy and excision of the involved digital fascia is the best method. If there is severe extension of contracture, Z-plasties, full-thickness grafts, or operation at the articular capsules or ligaments may be necessary. A documentation model and control of the surgical success are demonstrated.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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