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  • Electronic Resource  (16)
  • 2000-2004  (5)
  • 1985-1989  (10)
  • 1955-1959  (1)
  • 1
    Electronic Resource
    Electronic Resource
    ZnSe homoepitaxial layers grown at very low temperature by atmospheric pressure metalorganic vapor-phase epitaxy (1989)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 65 (1989), S. 2728-2733 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: ZnSe homoepitaxial layers with high crystalline quality were grown on (100) ZnSe substrates (grown by the iodine vapor transport method) between 190 and 250 °C. The surface morphologies of homoepitaxial layers (homoepilayers) grown below 250 °C were all mirrorlike. The concentration of self-activated (SA) centers is related to the growth temperature. The band-edge photoluminescence (PL) intensity increases drastically with increasing temperature from 190 up to 210 °C, decreases above 210 °C, and the SA-PL intensity increases monotonically as the growth temperature increases. The mechanism of suppressing the occurrence of SA centers below 250 °C is assumed that the concentration of Zn vacancies diffused from the highly iodine-doped ZnSe substrates into the ZnSe homoepilayers reduces at this temperature region. The SA-PL intensity of the ZnSe homoepilayer with the strongest band-edge emission (grown at 210 °C) is the same or weaker than that of the best ZnSe heteroepitaxial layer (heteroepilayer). Below 200 °C, the FWHM of the ZnSe (400) diffraction is 14 arcsec which is the best value we have ever obtained, though the growth temperature seems to be too low to maintain the crystalline quality. The comparison on the crystalline quality with the ZnSe heteroepilayers is discussed in detail from the viewpoints of the epitaxial growth mechanism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.342760
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  • 2
    Electronic Resource
    Electronic Resource
    A plane-grating monochromator for radiometric calibration : INTERNATIONAL CONFERENCE ON SYNCHROTRON RADIATION INSTRUMENTATION (1989)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 60 (1989), S. 2089-2092 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A new plane-grating monochromator and calibration chamber were constructed for the radiometric calibration of plasma diagnostic devices. The monochromator is designed to cover a wavelength range of 1.8–238 nm with moderate resolving power of 500±200 in λ/Δλ. To check the performance of the monochromator, spectral distribution and resolution were measured by experiments on photoemission from solids and photoionization of rare gases. The characterization of multilayer reflectors by the use of this beamline is demonstrated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1140833
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  • 3
    Electronic Resource
    Electronic Resource
    X-ray optical properties of molybdenum-carbon, molybdenum-silicon, and nickel-carbon multilayers : International conference on synchrotron radiation instrumentation (1989)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 60 (1989), S. 2006-2009 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We have fabricated multilayer reflectors of molybdenum-carbon, molybdenum-silicon, and nickel-carbon for x rays of 1–200 A(ring) with an electron beam evaporation method in ultrahigh vacuum. The multilayers were deposited on flat and figured substrates of float glass and superpolished glass with a surface roughness of 2–3 A(ring) (rms). The thickness of a layer pair and the number of layer pairs were 30–100 A(ring) and 10–20, respectively. The x-ray characteristics of these multilayer reflectors were evaluated in the 1.5–200 A(ring) region with characteristic x rays (Cu-Kα, Si-Kα, Al-Kα, and C-Kα) and monochromatized synchrotron radiation. Peak reflectivities of molybdenum-carbon were found to be 70% at Cu-Kα and 40% at Al-Kα in grazing incidence and those of molybdenum-silicon to be more than 30% in the 150–170 A(ring) band in near-normal incidence. On the basis of these experimental results, the x-ray optical properties of multilayers are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1140861
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  • 4
    Electronic Resource
    Electronic Resource
    Superpolished single-crystal molybdenum mirror for x-ray ultraviolet to x-ray radiation (1988)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 52 (1988), S. 1111-1113 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: High-quality single-crystal molybdenum (Mo) fabricated by a secondary recrystallization method has been polished with a new polishing technique. The superpolished surface of the Mo single crystal has a surface roughness of 3.5 A(ring) rms. This superpolished single-crystal Mo has been used for a high-power electron beam pumped argon excimer laser (λ=126 nm) as a cavity mirror. Peak output power of more than 3 MW has been achieved without any damage to the mirror surface.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.99177
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  • 5
    Electronic Resource
    Electronic Resource
    A theoretical study of thermal reactions of bicyclo[2.1.0]pent-2-ene (1987)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 109 (1987), S. 4157-4162 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00248a005
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  • 6
    Electronic Resource
    Electronic Resource
    Cysteinyl leukotriene-dependent interleukin-5 production leading to eosinophilia during late asthmatic response in guinea-pigs (2002)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 32 (2002), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Allergic airway eosinophilia is suppressed by cysteinyl leukotriene (CysLT) receptor (CysLT1 receptor) antagonists in several species including humans and guinea-pigs, suggesting that CysLTs are directly or indirectly involved in induction of the response.Objective We examined the effect of CysLT antagonists (pranlukast and MCI-826) on antigen inhalation-induced eosinophilia in peripheral blood and lung, and on IL-5 activity in serum during late increase of airway resistance (late asthmatic response, LAR) in sensitized guinea-pigs.Methods Guinea-pigs inhaled ovalbumin (OVA) + Al(OH)3 and OVA mists alternately for sensitization and challenge, respectively, once every 2 weeks. At the fifth challenge, the effects of CysLT antagonists and an anti-IL-5 antibody (TRFK-5) on the occurrence of LAR, and blood and lung eosinophilia, which appeared at 5 h after challenge, were examined. The time-course of IL-5 activity in the serum after the challenge was evaluated by measuring in vitro‘eosinophil survival prolongation activity’. The influence of CysLT antagonists on IL-5 activity was assessed.Results CysLT antagonists and TRFK-5 completely abolished blood and lung eosinophilia. LAR was suppressed by both MCI-826 and TRFK-5 by 40–50%. Sera obtained from sensitized, challenged animals 3 h and 4 h after challenge induced an obvious prolongation of eosinophil survival. The activity of the sera was completely neutralized by prior exposure to TRFK-5, suggesting that it reflected IL-5 activity. Increased IL-5 activity in the serum was inhibited by both pranlukast and MCI-826 by over 90%.Conclusions CysLTs produced after antigen provocation sequentially induced IL-5 production from some immune component cells via CysLT1 receptor activation. Thus, it is likely that CysLTs indirectly cause antigen-induced eosinophilia through IL-5 production.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.0954-7894.2002.01329.x
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  • 7
    Electronic Resource
    Electronic Resource
    Blockade of superoxide generation prevents high-affinity immunoglobulin E receptor-mediated release of allergic mediators by rat mast cell line and human basophils (2002)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 32 (2002), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Previous studies have shown that rat peritoneal mast cells and mast cell model rat basophilic leukaemia (RBL-2H3) cells generate intracellular reactive oxygen species (ROS) in response to antigen challenge. However, the physiological significance of the burst of ROS is poorly understood.Objective The present study was undertaken to investigate the role of superoxide anion in mediator release in rat and human cell systems.Methods RBL-2H3 cells were directly stimulated with anti-rat FcεRI α-subunit monoclonal antibody (mAb). For the analysis of human cell system, leucocytes were isolated by dextran sedimentation from healthy volunteers or from patients, and challenged either with anti-human FcεRI mAb or with the relevant antigens. Superoxide generation was determined by chemiluminescence-based methods. The releases of histamine and leukotrienes (LT)s were determined by enzyme-linked immunosorben assay (ELISA).Results Cross-linking of FcεRI on RBL-2H3 cells or on human leucocytes from healthy donors by the anti-FcεRI mAb resulted in a rapid generation of superoxide anion, as determined by chemiluminescence using superoxide-specific probes. Similarly, leucocytes from patients generated superoxide anion in response to the challenge with the relevant allergen but not with the irrelevant allergen. Furthermore, diphenyleneiodonium (DPI), a well-known inhibitor of flavoenzymes suppressed the superoxide generation and the release of histamine and LTC4 induced by the anti-FcεRI mAb or by allergen in parallel.Conclusion These results indicate that both RBL-2H3 cells and human basophils generate superoxide anion upon FcεRI cross-linking either by antibody or by allergen challenge and that blockade of the generation prevents the release of allergic mediators. The findings strongly support the role of superoxide generation in the activation of mast cells and basophils under both physiological and pathological conditions. The findings suggest that drugs regulating the superoxide generation have potential therapeutic use for allergic disorders.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.0954-7894.2002.01263.x
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  • 8
    Electronic Resource
    Electronic Resource
    Periodontal status and serum antibody titers for Porphyromonas gingivalis fimbriae in a rural population in Japan (2001)
    Copenhagen : Munksgaard International Publishers
    Journal of clinical periodontology 28 (2001), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background, aims: The present study was undertaken to assess the periodontal status of a rural Japanese population and to study the correlation between the periodontal status and the serum antibody titers for Porphyromonas gingivalis (Pg) fimbriae.Method: A total of 236 individuals were examined for their periodontal conditions by the use of the community periodontal index for treatment needs (CPITN), and serum antibody titers for Pg fimbriae in their peripheral blood samples were evaluated using the enzyme-linked immunosorbent assay.Results: There was a substantially larger proportion of edentulous subjects in the age group older than 60 years. The remaining teeth were 24.1, 23.2, 11.1 and 10.1 per person in the 40–49, 50–59, 60–69 and 〈inlineGraphic alt="geqslant R: gt-or-equal, slanted" extraInfo="nonStandardEntity" href="urn:x-wiley:03036979:JCPE280311:ges" location="ges.gif"/〉70 age groups, respectively. The % of sextants with a CPITN code of missing sextant (MS) increased towards elderly and reached 〉60% in the age group of 〈inlineGraphic alt="geqslant R: gt-or-equal, slanted" extraInfo="nonStandardEntity" href="urn:x-wiley:03036979:JCPE280311:ges" location="ges.gif"/〉70 years, as the % of the CPITN 2, 1 or 0 sextant decreased. The % of CPITN 4 and 3 sextants did not differ between different age groups and were about 6–8% and 15–20%, respectively. The % of CPITN 1 or 0 sextants was higher in female subjects than in male subjects in the 60–69 and 〈inlineGraphic alt="geqslant R: gt-or-equal, slanted" extraInfo="nonStandardEntity" href="urn:x-wiley:03036979:JCPE280311:ges" location="ges.gif"/〉70 age groups, while the % of CPITN 4 or 3 sextants was higher in male subjects than in female subjects in all age groups. There was no significant difference between various age groups in the mean serum antibody titers for Pg fimbriae. The mean anti-Pg fimbriae antibody titers was significantly higher for the subjects with a maximum CPITN code 4 (max.-CPITN 4 subject) than for the subjects with lower maximum CPITN codes. The antibody titers varied extensively among the max.-CPITN 4 or 3 subjects, but not among the max.-CPITN 2/1/0 or MS subjects.Conclusions: The present study demonstrated that tooth loss is a remarkable event in elderly subjects and that oral prophylaxis and mechanical debridement should be mandatory in the population examined. It was also demonstrated that the serum antibody titers against Pg fimbriae could be useful for screening individuals with moderate to severe periodontitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-051x.2001.028003264.x
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  • 9
    Electronic Resource
    Electronic Resource
    Blastogenic response and immunoglobulin production by inflamed gingival lymphocytes from dogs (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 23 (1988), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The present study evaluated blastogenic responses and immunoglobulin production (IgG, IgM) by inflamed gingival lymphocytes from dogs. The excised tissues were cut finely, digested in collagenase for 60 min, then passed through a mesh, teased with a 24 G needle several times and centrifuged over a ficoll gradient. Responses to PHA, Con-A and PWM were assessed using peripheral blood lymphocytes (PBLs) and submandibular lymph node cells (SNLs) as controls. Blastogenesis was evaluated from the uptake of 3H-thymidine and the presence of IgG and IgM in culture supernatants was quantified using ELISA. The extraction procedure resulted in a mean 2.09 ± 0.44 × 105 lymphocytes per 100 mg tissue (wet weight). These cells had a mean viability of 84.4 ± 3.0%. The responses of PBLs and SNLs to PHA, Con-A and PWM were substantial, as expected, while the responses of gingival lymphocytes to any mitogen remained at the level of unstimulated lymphocytes. However, gingival lymphocytes produced and secreted IgG and IgM. IgG production by gingival lymphocytes was elevated when compared with those of PBLs and SNLs, while IgM production by gingival lymphocytes was less than PBLs and SNLs. The responses of PBLs and SNLs are not parallel to the response of gingival lymphocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1988.tb01425.x
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  • 10
    Electronic Resource
    Electronic Resource
    Muscular Exercise and Adrenal 17-Hydroxycorticosteroid Secretion in Dogs (1958)
    [s.l.] : Nature Publishing Group
    Nature 181 (1958), S. 715-715 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] For collecting the adrenal venous blood under physiological condition, the lumbar route method of Satake, Sugawara and Watanabe4 was employed. The dorsal spinal roots corresponding to the surgical operation area were cut under 'Evipan'-sodium and ether narcosis and about three weeks or more later ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/181715a0
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