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  • Electronic Resource  (2)
  • 2000-2004  (2)
  • 1940-1944
  • 1930-1934
  • Key words:ACR core set – Rheumatoid arthritis – SF-36  (1)
  • Keywords:Clamping; Feature salience ranking; Input impact; Neural networks  (1)
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  • Electronic Resource  (2)
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  • 2000-2004  (2)
  • 1940-1944
  • 1930-1934
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Neural computing & applications 9 (2000), S. 101-112 
    ISSN: 1433-3058
    Keywords: Keywords:Clamping; Feature salience ranking; Input impact; Neural networks
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: For a variety of reasons, the relative impacts of neural-net inputs on the output of a network’s computation is valuable information to obtain. In particular, it is desirable to identify the significant features, or inputs, of a data-defined problem before the data is sufficiently preprocessed to enable high performance neural-net training. We have defined and tested a technique for assessing such input impacts, which will be compared with a method described in a paper published earlier in this journal. The new approach, known as the ‘clamping’ technique, offers efficient impact assessment of the input features of the problem. Results of the clamping technique prove to be robust under a variety of different network configurations. Differences in architecture, training parameter values and subsets of the data all deliver much the same impact rankings, which supports the notion that the technique ranks an inherent property of the available data rather than a property of any particular feedforward neural network. The success, stability and efficiency of the clamping technique are shown to hold for a number of different real-world problems. In addition, we subject the previously published technique, which we will call the ‘weight product’ technique, to the same tests in order to provide directly comparable information.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-9949
    Keywords: Key words:ACR core set – Rheumatoid arthritis – SF-36
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The aim of the study was to show that the SF-36 is a practical tool for use on outpatients with RA, to examine the relationship between the SF-36 and indices of outcome in RA, and to compare the results with population norms and other disease states. Eighty-six consecutive RA patients attending the Haywood Hospital in Stoke-on-Trent and starting or changing second-line therapy were enrolled. Disease outcome was assessed using the American College of Rheumatology core set and all subjects completed the SF-36 health questionnaire. The cohort had moderately active disease (median ESR 46) and appreciable disability (median HAQ 1.875). Impairment of health status was moderate to marked by the SF-36, with significant differences from population norms and chronic disease states such as low back pain. Good correlations were observed between HAQ and physical function (r〉0.75, p〈10–6) and HAQ and social function (r〉0.61, p〈10–6). In contrast, SF-36 scales for physical and emotional role showed no association with activity measures. We concluded that, SF-36 is a practical tool for use in patients with RA. HAQ is associated with its physical and social function scales. Other SF-36 scales, such as physical and emotional role, are not associated with activity core set measures; this suggests different information is involved. RA has a considerable impact on health status compared to other diseases.
    Type of Medium: Electronic Resource
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