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  • Electronic Resource  (23)
  • 1995-1999  (20)
  • 1980-1984  (2)
  • 1950-1954  (1)
  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 77 (1995), S. 5125-5129 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The adsorption of oxygen on H-terminated Si(100) surfaces has been investigated by high-resolution electron energy loss spectroscopy (HREELS). Adsorptions of atomic oxygen occur even at room temperature. Si-OH stretching and Si-O-Si (B1) vibrational modes are observed in HREELS spectra, which indicates that atomic oxygen is adsorbed on sites of Si—H bonds and Si—Si back bonds. On the other hand, H-terminated surfaces are very stable for molecular oxygen, which cannot adsorb until 380 °C on the surface. A dissociative adsorption of molecular oxygen is observed above 380 °C and the activation energy of the adsorption is 2.0 eV at 380–450 °C. This value coincides with the desorption energy of hydrogen atoms from a Si(100) surface with the monohydride phase. These results indicate that the dangling bonds are essential to the adsorption of molecular oxygen on Si(100) surfaces. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Three monoclonal antibodies HU-11, HU-32, and HU-33, which recognize two distinct polymorphic determinants of human class II antigens, were found to cross-react with rat B cells carrying an RT1B region-associated specificity Ba-2.6. This is the first report demonstrating that xenoimmune antibodies raised against polymorphic determinants of human class II antigens are able to detect polymorphic determinants of class II antigens in a third party species.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 318-320 (Oct. 1999), p. 681-686 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 45 (1982), S. 243-252 
    ISSN: 1432-1106
    Keywords: Amblyopia ; Strabismus ; Penalisation ; Ocular dominance ; Perikaryal size
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Six cats were reared with surgically produced squint or atropinisation of one eye during the sensitive period of development. Five cats were reared without any ocular interference but in the same environment as the experimental cats. Four of these normally reared cats provided control data for perikaryal size. When the cats were 5–8 months old, the ocular dominance distribution of cells in area 17 of the visual cortex was determined, and measurements of visual acuity of cells in the LGN receiving inputs from the area centralis were carried out. Following the neurophysiological experiments, the perikaryal sizes of LGN cells receiving fibres from the area centralis of the left and right eye were measured from Nissl stained sections of the brain of each cat. Cats which showed greater amblyopia (loss of acuity) of LGN cells driven from the area centralis of the experimental eye, showed a greater degree of apparent ‘shrinkage’ of Nissl stained LGN cells and a greater proportion of cortical cells excited by the control eye than by the experimental eye. All experimental cats showed a loss of binocularly driven cells, regardless of whether their LGN cells were amblyopic or not, and whether they had ‘shrunk’ or not. However, when LGN cell amblyopia was present, the degree of amblyopia and ‘shrinkage’ of the LGN cells were correlated with the degree of loss of binocular cells also.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1437-7772
    Keywords: Patterns of Care ; Study ; Esophageal cancer Radiation therapy ; The elderly ; Parameter survey ; Age
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background. In Japan, the elderly population is growing rapidly, and therefore, so is the number of cancer patients who are not good candidates for aggressive surgery or chemotherapy. Radiation therapy offers excellent potential for the treatment of such patients, with minimal invasion and functional preservation. A Patterns of Care Study (PCS) examined the parameters of treatments used for patients with esophageal cancer to determine nationwide variations by age. Methods. From July 1996 through February 1997, external nationwide PCS audits were performed for 29 institutions. Medical charts were reviewed for 455 patients with thoracic esophageal cancer treated between 1992 and 1994. The parameters of treatments used for these patients were compared between those aged ≥75 years (elderly; n = 113) and those aged 〈75 years (yourger; n = 342). Results. Surgery was used in 49% of the younger group and in 17% of the elderly group (P 〈 0.0001) while chemotherapy was used in 48% of the younger and 24% of the older group (P 〈 0.0001). The ratio of non-surgery group with radiation therapy increased significantly from 49% to 82% (P 〈 0.0001). Approximately 70% of the non-surgery patients received an external radiation dose of more than 60Gy, even in the elderly (P = 0.3001). Preliminary results showed no significant difference in survival between the two age groups (P = 0.5559). Conclusions. The use of radiation therapy in elderly people with esophageal cancer has increased markedly. The PCS provided important information about variations in radiotherapy parameters in patients with esophageal cancer in relation to age. Such information should be useful for future prospective studies of the elderly.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Nutrient cycling in agroecosystems 49 (1997), S. 287-293 
    ISSN: 1573-0867
    Keywords: carbon cycling ; carbon dioxide sequestration ; carbon sink ; modeling ; terrestrialecosystem
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Major conclusions from our two projects focussing on carbon cycling in terrestrial ecosystems are as follows: 1) A rural system or a farmland system tends to be a source of carbon dioxide. However, it was possible to increase carbon dioxide sequestration in soil by changing soil or paddy/upland-field management systems. 2) A model simulation showed that a carbon budget in a natural forest was balanced before cutting but the large minus (source) was observed just after cutting. But the balance changed from minus to plus (sink) in 10 years after cutting. Nearly the same amounts of carbon as that stocked in the timbers before harvesting accumulated in 70-80 years after the cutting. 3) These results indicate the possibility of soils in terrestrial ecosystems as the major sink of atmospheric carbon dioxide.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0533
    Keywords: Key words HTLV-I ; HTLV-I-associated ; myelopathy/tropical spastic paraparesis ; Rat model ; Apoptosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In seropositive HTLV-I carrier rats of the WKAH strain inoculated with 2 × 107 MT-2 cells at 3–6 months of age, chronic progressive myeloneuropathy, tentatively designated as HTLV-I-associated myelopathy (HAM) rat disease, occurred when the rats were 19–23 months old. Clinical and pathological findings were basically identical to those of seronegative HAM rats of the same strain neonatally inoculated with MT-2 cells. It appears that a high dose of MT-2 cells (108 cells) is more effective for the induction and acceleration of HAM rat disease. Seronegative and seropositive carriers of other strains (F344, ACI, and LEW), WKAH rats inoculated with HUT-78 (a human T cell line without HTLV-I infection), and untreated WKAH rats at comparable ages did not develop HAM rat disease, thereby indicating that development of this disease is caused by HTLV-I infection and is under strict genetic restriction of the host strain. Chronological examination of HAM rat disease induced by 107 MT-2 inoculation into newborn rats showed that the spinal cord lesion began to develop by 12 months of age. T cells were absent in the affected spinal cord throughout the disease process. There was morphological evidence of apoptotic death of oligodendrocytes in the affected spinal cord. Apoptosis was also confirmed by the specific nick end labeling of the nuclear fragmentation in situ, and the apoptotic oligodendrocytes confined to the demyelinating foci, and the number of apoptotic cells positively correlated with severity of the spinal cord lesion. The collective evidence suggests that the major pathogenetic pathway of HAM rat disease appears to be closely related to apoptotic death of the oligodendrocytes, directly or indirectly associated with HTLV-I infection.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0533
    Keywords: HTLV-I ; HTLV-I-associated ; myelopathy/tropical spastic paraparesis ; Rat model ; Apoptosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In seropositive HTLV-I carrier rats of the WKAH strain inoculated with 2×107 MT-2 cells at 3–6 months of age, chronic progressive myeloneuropathy, tentatively designated as HTLV-I-associated myelopathy (HAM) rat disease, occurred when the rats were 19–23 months old. Clinical and pathological findings were basically identical to those of seronegative HAM rats of the same strain neonatally inoculated with MT-2 cells. It appears that a high dose of MT-2 cells (108 cells) is more effective for the induction and acceleration of HAM rat disease. Seronegative and seropositive carriers of other strains (F344, ACI, and LEW), WKAH rats inoculated with HUT-78 (a human T cell line without HTLV-I infection), and untreated WKAH rats at comparable ages did not develop HAM rat disease, thereby indicating that development of this disease is caused by HTLV-I infection and is under strict genetic restriction of the host strain. Chronological examination of HAM rat disease induced by 107 MT-2 inoculation into newborn rats showed that the spinal cord lesion began to develop by 12 months of age. T cells were absent in the affected spinal cord throughout the disease process. There was morphological evidence of apoptotic death of oligodendrocytes in the affected spinal cord. Apoptosis was also confirmed by the specific nick end labeling of the nuclear fragmentation in situ, and the apoptotic oligodendrocytes confined to the demyelinating foci, and the number of apoptotic cells positively correlated with severity of the spinal cord lesion. The collective evidence suggests that the major pathogenetic pathway of HAM rat disease appears to be closely related to apoptotic death of the oligodendrocytes, directly or indirectly associated with HTLV-I infection.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 174 (1954), S. 698-700 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Rhodamine B rat sarcoma4 and fructose mouse sarcoma6 were used for tissue culture experiments. The roller tube technique was used and the cover-slip technique in Porter flasks was employed for staining cells grown in tissue culture. Suitable pieces of tumour tissues were grown directly on the glass ...
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  • 10
    ISSN: 1432-0428
    Keywords: Keywords Pioglitazone ; muscle TNF-α ; sphingomyelinase ; insulin resistance ; Wistar fatty rat.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In order to evaluate the relationship between tumour necrosis factor-α (TNF-α) level in muscle and metabolic abnormalities in obesity and diabetes mellitus, pioglitazone, a novel insulin-sensitizing agent, was administered to Wistar fatty rats and time-dependent changes in muscle TNF-α content and plasma indicators of diabetes and obesity were measured. Wistar fatty rats were hyperglycaemic, hyperlipidaemic and hyperinsulinaemic, and their plasma and muscle TNF-α levels were two or more times higher than those in normal lean rats at 16 weeks of age. When pioglitazone was administered to fatty rats at a dose of 3 mg · kg–1· day–1, the plasma triglyceride level and TNF-α levels in plasma and muscle decreased time-dependently, and reached the levels of lean rats within 4 days. Plasma glucose and insulin levels also decreased time-dependently with pioglitazone, but on day 4, these levels were still much higher than the levels in lean rats. Neutral sphingomyelinase (SMase) activity in muscle of fatty rats was two times higher than that in lean rats and was lowered to the level of that in lean rats by 4 days' pioglitazone administration. The plasma leptin level in fatty rats was 8 times higher than that in lean rats, but pioglitazone did not affect the level during the 4-day administration period. These results suggest that an increase in TNF-α production and subsequent activation of SMase in muscle leads to metabolic abnormalities in obesity and diabetes and that antidiabetic activity of pioglitazone is deeply associated with the suppression of TNF-α production. [Diabetologia (1998) 41: 257–264]
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