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  • Electronic Resource  (3)
  • 1995-1999  (1)
  • 1980-1984  (2)
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  • Electronic Resource  (3)
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  • 1
    Electronic Resource
    Electronic Resource
    Peyer's Patches in Murine AIDS: Dissociation Between Lymphoproliferation and Anergy (1997)
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Scandinavian journal of immunology 45 (1997), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: RadLV-Rs infection induces a murine immunodeficiency syndrome associated with a dramatic enlargement of spleen and lymph nodes. Surprisingly, the lymphoproliferation excludes thymus and Peyer's patches (PP). To understand the cellular interactions underlying lymphoproliferation further, the authors investigated the fate of PP in RadLV-Rs infected mice. The atrophy of PP was mostly due to the depletion of B cells, while the proportion of CD4+ and CD8+ T cells was increased. Nevertheless, B cell phenotype was modified with the emergence of lymphocytes with a low expression of B220 in infected PP. T cells characterized by a memory/activated phenotype in control PP did not undergo phenotypical changes after viral infection (i.e. regarding Thy-1 and CD44 expression). Despite the absence of lymphoproliferation, PP T and B cells displayed altered responses to mitogens in vitro. Finally, alterations of the expression of adhesion molecules and vascular addressins could not explain the atrophy of PP by a reduced homing to this lymphoid site. B cells and T cells from normal PP are clearly different from lymph nodes (LN) lymphocytes. The authors propose that the particular functional state which characterizes PP lymphocytes influences the B cell/T cell crosstalk necessary for RadLV-Rs-induced lymphoproliferation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3083.1997.d01-390.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Pre-embedding immunohistochemistry as an approach to high resolution antigen localization at the light microscopic level (1981)
    Springer
    Histochemistry and cell biology 72 (1981), S. 173-190 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Pre-embedding immunohistochemistry with subsequent embedding in hydroxypropyl methacrylate enables one to obtain high resolution staining of antigens in 1 μ tissue sections. A routine method using formaldehyde fixation, methanol permeation, and an indirect method with fluoresceinlabeled second antibody is described. This method is compared with other pre-embedding staining procedures. To illustrate the method the mouse small intestine was chosen as a model and stained with antibodies to tubulin, actin, and fibronectin. Some anticipated and some unusual staining patterns were found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00517131
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    A generalized Hill-Wheeler ansatz (1984)
    Springer
    The European physical journal 318 (1984), S. 223-229 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The Hill-Wheeler ansatz for the total wave function, within the Generator Coordinate Method framework, is generalized by recourse to the theory of distributions. The ensuing approach allows one to obtain a basis that spans the collective subspace, without having to deal explicitly with the eigenvectors and eigenvalues of the overlap kernel. Applications to an exactly soluble model and anharmonic vibrations illustrate the present treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01413473
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    Paper (German National Licenses)
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