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  • Electronic Resource  (2)
  • 1985-1989  (2)
  • Benigne Systemerkrankung  (1)
  • 27.60.+j
  • locomotion
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 369 (1986), S. 239-245 
    ISSN: 1435-2451
    Keywords: Benign systemic disorder ; Spleen ; Splenectomy ; Benigne Systemerkrankung ; Milz ; Splenektomie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die benignen Systemerkrankungen mit Milzbeteiligung umfassen haematologische Krankheiten, Speicherkrankheiten, Kollagenosen, Morbus Boeck, Infektionskrankheiten, Parasitosen und sonstige mit Blutabflußstörungen der Milz einhergehende Leiden. 4/5 der Fälle betreffen die haematologischen Erkrankungen des erythrocytären, thrombocytären und lymphatischen Systems sowie myeloproliferative und aplastische Syndrome. 227 von 1214 Splenektomien der letzten 20 Jahre wurden bei benignen Systemerkrankungen durchgeführt. Der ausgeprägte funktionelle und mechanische Hypersplenismus ergibt in der Regel die Indikation zur Operation. Die einzelnen Indikationen, die internistische Vorbehandlung und die Kombination mit nicht chirurgischen Maßnahmen werden dargestellt.
    Notes: Summary The benign systemic disorders with involvement of the spleen are divided into haematologic diseases, thesaurismosis, collagenosis, morbus Boeck, infectious diseases, parasitosis and others. 4/5 of the cases are haematologic diseases of the erythrocytic, the thrombocytic and lymphatic system as well as myeloproliferative and aplastic syndromes. 227 of 1214 splenectomies of the last 20 years were done in benign systemic diseases. The functional and mechanical hypersplenism as a rule is the cause for operation. The specific indications, the medical pretreatment and the combination of surgery and nonsurgical measures are discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 5 (1985), S. 447-461 
    ISSN: 0886-1544
    Keywords: chemokinesis ; orthokinesis ; klinokinesis ; polymorphonuclear leucocytes ; locomotion ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Evidence is presented to show that klinokinesis, which was previously demonstrated in bacteria and amoeba only, may also occur in metazoan cells. The chemotactic peptide formyl-Met-Leu-Phe (fMLP) elicited orthokinetic and klinokinetic responses of human blood-borne polymorphonuclear leucocytes (PMNs) under the test conditions used. Increased speed (orthokinesis) was due to an increase in the proportion of migrating cells as well as in the speed of the locomoting subset. The klinokinetic effect was manifested by a decrease in the klinolocomotion index, the mean angle of changes in direction ≥ 90°, and the frequency of turns ≥ 90°. The klinolocomotion index was inversely related to speed. This explains the synergistic effect of klinokinesis and orthokinesis in this system. Colchicine alone had and orthokinetic effect which was exclusively due to alterations in the proportion of migrating cells and it altered the turning behaviour without exerting a klinokinetic effect. However, colchicine had marginal orthokinetic and klinokinetic effects on fMLP-stimulated cells resulting in reduced translocation. The relationship between klinokinesis and mean angle or frequency of turns has been analysed. Klinokinesis was a substantial though not the major element of the chemokinetic response to fMLP under the conditions used. No other metazoan cells have been shown to possess such a complete pattern of responses, including orthokinesis, klinokinesis, and chemotaxis, which regulate locomotion.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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