ISSN:
1573-2568
Keywords:
opioids
;
naloxone
;
gastrointestinal motility
;
breath test
;
obesity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Orocecal transit time was assessed with lactulose hydrogen breath test in 12 obese patients during intravenous infusion of placebo or naloxone 40 μg/kg/hr given in randomized order and in double-blind conditions. Transit time was also evaluated in 22 healthy controls. Orocecal transit was significantly (P〈0.01) longer in the obese patients during placebo treatment (median 130, range 100–200 min) than in the healthy controls (median 75, range 40–170 min). Compared with placebo, transit time in the obese subjects was delayed (P〈0.05) during naloxone treatment (median 150, range 100–230 min).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01536325
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