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  • 1
    Digitale Medien
    Digitale Medien
    β-adrenoceptor blockade and migraine (1982)
    USA/Oxford, UK : Blackwell Science Ltd
    Cephalalgia 2 (1982), S. 0 
    Details
    ISSN: 1468-2982
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Except for propranolol, no other b-blocker has been studied thoroughly in the prophylaxis of migraine. Of those studied, propranolol, atenolol and timolol were shown to be useful in double-blind clinical trials. The mode, or even the site of action of these drugs is unknown. Possible mechanisms of action are peripheral vascular effects, a central action, 5-HT antagonism, an anxiolytic effect and a multifactorial action. The only common property of the successful drugs is lack of partial agonist activity and their profiles do not fully support any of the above hypotheses. Trials of drugs in the prophylaxis of migraine have in general been unsatisfactory due to the difficulty in controlling many variables. b-blockers with differing properties offer an opportunity to define the properties necessary for anti-migraine activity and perhaps shed light on the pathogenesis of migraine.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1468-2982.1982.0201033.x
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  • 2
    Digitale Medien
    Digitale Medien
    Nuclear magnetic resonance study of acid-base interactions for the chloranil electrode system in acetonitrile (1972)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 76 (1972), S. 246-248 
    Details
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/j100646a018
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  • 3
    Digitale Medien
    Digitale Medien
    Experiments to Assess the Hydraulic Efficiency of Well Screens (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 21 (1983), S. 0 
    Details
    ISSN: 1745-6584
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Energietechnik , Geologie und Paläontologie
    Notizen: The hydraulic properties of commercial well screens were investigated to determine which screen design features affected head loss. The test program began with laboratory experiments and continued as a field-scale experiment with the installation of a well field in the Thames Valley Gravel Aquifer.The laboratory experiments indicated that, for all practical purposes, the head loss attributable to all of the screens tested was negligible. The experimental head loss, however, did vary from screen to screen, particularly at high intake velocities, and the screens could be ranked on the basis of their hydraulic efficiencies. This efficiency hierarchy is explained tentatively in terms of the screen construction methods and slot geometry. The field experiments showed that the hydraulic performance of all well screens is independent of screen design provided that the open area of the screen is above about 10%. The field experiments also indicated that the development capacity of a screen in a gravel aquifer is not wholly dependent on screen design, but that progressive development does increase the hydraulic efficiency of a well.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1745-6584.1983.tb00722.x
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  • 4
    Digitale Medien
    Digitale Medien
    Components of A Jungian Theoretical Orientation (1984)
    Oxford, UK : Blackwell Publishing
    The @journal of analytical psychology 29 (1984), S. 0 
    Details
    ISSN: 1468-5922
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Psychologie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1465-5922.1984.00067.x
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  • 5
    Digitale Medien
    Digitale Medien
    Carbon cycle changes of the Zechstein Sea: isotopic transition zone in the Marl Slate (1982)
    [s.l.] : Nature Publishing Group
    Nature 297 (1982), S. 389-390 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] On the basis of measurements of carbon isotopes on rocks of various ages, early models assumed that the mean S13C (carbonate) values were constant3"6. In recent years, however, descriptions of secular variation of S13C values in carbonate rocks during the Mesozoic7'8 and Cenozoic9*10 have ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/297389a0
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  • 6
    Digitale Medien
    Digitale Medien
    Ultrastructure of Synaptic Vesicle Formation in Cerebral Cortex (1973)
    [s.l.] : Nature Publishing Group
    Nature 242 (1973), S. 57-59 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] Fig. 1 Cortex extracellular space is filled with electron dense reaction product of horseradish peroxidase (HRP) 1 h after sub-arachnoid application. Presynaptic terminals show many of their synaptic vesicles filled with tracer and two vesicles (arrows) are intimately associated with the ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/242057a0
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  • 7
    facet.materialart.
    Unbekannt
    Tito's Army (1971)
    London : Periodicals Archive Online (PAO)
    The RUSI journal. 116 (1971:Sept.) 63 
    Details
    ISSN: 0307-1847
    Thema: Politikwissenschaft
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:p225-1971-116-00-000050
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  • 8
    Digitale Medien
    Digitale Medien
    The bioavailability of oral intermediate-dose methotrexate (1984)
    Springer
    Cancer chemotherapy and pharmacology 13 (1984), S. 91-94 
    Details
    ISSN: 1432-0843
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The oral bioavailability of methotrexate is variable and may be dose-dependent. The absorption of ‘interval’ oral methotrexate, which is given between cycles of chemotherapy, is unknown. The bioavailability of oral methotrexate has been studied in eight patients, acting as their own controls, to assess the effect of subdivision of the dose, the formulation, and the timing of the methotrexate within the chemotherapy cycle. The mean bioavailability for all the oral methods of administration was 28.2%±3.7% compared with the same dose given IV. Absorption was uninfluenced by subdivision of the dose, liquid or tablet formulation, or administration on day 1 or day 10 of the chemotherapy cycle.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00257121
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  • 9
    Digitale Medien
    Digitale Medien
    The efficiency of protective gloves used in the handling of cytotoxic drugs (1984)
    Springer
    Cancer chemotherapy and pharmacology 12 (1984), S. 151-153 
    Details
    ISSN: 1432-0843
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A range of clinical and industrial gloves have been evaluated to determine their ability to exclude penetration by cytotoxic drugs. Radiolabelled cyclophosphamide, methotrexate, daunomycin, cytosine arabinoside, and vincristine sulphate were studied in an equilibrium dialysis system in which the glove material was used as the dialysis membrane. The thicker gloves were the most effective, but very little drug crossed any of the gloves tested under laboratory conditions. Further studies to evaluate gloves in conditions of clinical use are now needed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00256536
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  • 10
    Digitale Medien
    Digitale Medien
    A study of the influence of pH on the buccal absorption and renal excretion of procainamide (1974)
    Springer
    European journal of clinical pharmacology 7 (1974), S. 287-289 
    Details
    ISSN: 1432-1041
    Schlagwort(e): Procainamide ; buccal absorption ; renal excretion ; urine ; pH
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Medizin
    Notizen: Summary The buccal absorption of procainamide was studied in 4 normal, male volunteers over a pH range of 5–11. In another investigation the same 4 volunteers collected their urine for 24 h after taking 250 mg of procainamide hydrochloride orally on 3 separate occasions, during which urine pH was uncontrolled, acidified by ammonium chloride ingestion or alkalinised by sodium bicarbonate ingestion. The procainamide remaining after buccal absorption and present in the urine samples was determined spectrophotometrically. It was found that neither the buccal absorption nor the renal excretion of procainamide was substantially altered by changes in pH.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00560346
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