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  • Electronic Resource  (8)
  • 1975-1979  (8)
  • 1955-1959
  • 1830-1839
  • Renin  (5)
  • Engineering General  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Inhibitory effect of tyramine-induced release of catecholamines on renin secretion (1978)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 303 (1978), S. 139-144 
    Details
    ISSN: 1432-1912
    Keywords: α-Adrenoceptors ; Renin ; Isoprenaline ; Tyramine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of the indirect sympathomimetic agent tyramine on the isoprenaline-induced increase in plasma renin concentration was investigated in conscious rats. Tyramine caused a dose-dependent decrease in the isoprenaline-induced elevation of plasma renin concentration. Pretreatment of the rats with reserpine abolished this effect of tyramine, indicating that tyramine released catecholamines which acted on the inhibitory adrenoceptors. Pretreatment with phenoxybenzamine, an α-adrenoceptor antagonist, also abolished the inhibitory effect of tyramine on renin release, indicating that α-adrenoceptors mediated the observed inhibition of renin release. In rats with chronically denervated kidneys tyramine did not inhibit renin release. It is concluded that catecholamines which are released from renal sympathetic nerve endings can suppress renin release by activating α-adrenoceptors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00508059
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Studies on the inhibitory effect of indomethacin and meclofenamate on the adrenalectomy-induced increase in plasma renin concentration (1979)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 309 (1979), S. 25-27 
    Details
    ISSN: 1432-1912
    Keywords: Adrenalectomy ; Renin ; Indomethacin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Bilateral adrenalectomy combined with a sodium-deficient diet caused a time-dependent increase in plasma renin concentration in rats. Seventy-two hours after adrenalectomy the inhibitors of prostaglandin biosynthesis indomethacin and meclofenamate diminished the plasma renin concentration by about 50%. This effect was independent of the amount of renin released. Indomethacin and meclofenamate fully retained their ability to reduce the plasma renin concentration when the renal sympathetic nerves or the macula densa cells of the kidneys no longer contributed to renin release. It is concluded that in adrenalectomized rats renal prostaglandins affect the baroreceptor-mechanism in the afferent arterioles and thus enhance renin release.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00498753
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    α-Adrenoceptor-mediated inhibitory effect of the sympathetic nervous system on the isoprenaline-induced increase in plasma renin concentration (1977)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 299 (1977), S. 77-82 
    Details
    ISSN: 1432-1912
    Keywords: α-Adrenoceptors ; Isoprenaline ; Renin ; Sympathetic nervous system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The importance of the sympatho-adrenal system for the isoprenaline-induced increase in plasma renin concentration was investigated in conscious rats. Ganglionic blockade by trimethidinium (10 mg kg−1) increased the dose-dependent elevation of plasma renin concentration induced by isoprenaline (0.03–0.48 μg kg−1 min−1). Also treatment of the rats with guanethidine (6 mg kg−1) or reserpine (2.5 mg kg−1, given 16 and 7 h prior to the experiments) further increased the effect of isoprenaline (0.5 μg kg−1 min−1) on plasma renin concentration. Unilateral renal denervation combined with contralateral nephrectomy doubled the effect of the β-sympathomimetic amine on renin release. The α-adrenoceptor antagonist phenoxybenzamine (3 mg kg−1) also enhanced the effect of isoprenaline on this parameter. It is concluded that apart from a stimulation of renin release via β-adrenoceptors the sympathetic nervous system may inhibit renin release via stimulation of α-adrenoceptors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00508641
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Suppression of isoprenaline-induced increase in plasma renin concentration by vasoconstrictors in rats with nonfunctioning Macula densa (1975)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 290 (1975), S. 315-321 
    Details
    ISSN: 1432-1912
    Keywords: Isoprenaline ; Renin ; Vasoconstrictors ; Macula densa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The mechanism of the increase in plasma renin concentration caused by the β-sympathomimetic agent isoprenaline has been further investigated. Rats were pretreated by occluding the left renal artery for 2 hrs, thus rendering the macula densa cells of this kidney nonfunctioning. After contralateral nephrectomy infusion of isoprenaline (1.5 μg/kg min) still caused a strong increase in plasma renin concentration. This increase was significantly suppressed by simultaneous infusion of angiotensin II (1.0 μg/kg min), the α-sympathomimetic amine phenylephrine (60 μg/kg min) or octapressin (10 mU/kg min). The results exclude any mediator-role of the macula densa receptors in the isoprenaline-induced release of renin. The possibility of a stimulation of renin release via the baroreceptors or a direct “secretomotoric” action of isoprenaline is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00510560
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Inhibition of the adrenalectomy-induced increase in plasma renin concentration by vasoconstrictor agents in rats (1976)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 294 (1976), S. 187-192 
    Details
    ISSN: 1432-1912
    Keywords: Adrenalectomy ; Renin ; Angiotensin II ; Felypressin ; Phenylephrine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Plasma renin concentrations in rats increase after bilateral adrenalectomy without sodium substitution. The effects of i.v. infused (asp1-β-amid, val5)-angiotensin II (1 μg/kg min), felypressin (phen2, lys8-vasopressin) (40 mU/kg min) and phenylephrine (30 μg/kg min) were investigated on the increase in plasma renin concentration. These effects of the agents were compared with their actions on blood pressure, heart rate and renal hemodynamics. In rats with destroyed macula densa cells the effect of bilateral adrenalectomy without sodium substitution was also studied. Adrenalectomy still increased the plasma renin concentration. Angiotensin II and felypressin, also depressed under these conditions the elevation of plasma renin concentration caused by adrenalectomy. The mechanism of the adrenalectomy-induced reinin release and its suppression by vasoconstrictor agents is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00507852
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Heat transfer during fluidized-bed coating (1975)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 9 (1975), S. 669-678 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A fully implicit numerical method for linear parabolic free boundary problems with coupled and integral boundary conditions is described. The partial differential equation and the boundary conditions are time discretized with the method of lines. An auxiliary function is introduced to remove the coupled and integral boundary conditions from the resulting free boundary problem for ordinary differential equations. Once separated boundary conditions are obtained, invariant imbedding is used to solve the free boundary problem numerically. The method is illustrated by solving the heat transfer equations for the fluidized-bed coating of a thin-walled cylinder.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620090313
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    An alternating direction method for multi-dimensional parabolic free surface problems (1977)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 11 (1977), S. 741-752 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A locally one-dimensional method (fractional step or alternating direction method) is used to approximate multi-dimensional free surface problems for the diffusion equation by a sequence of one-dimensional problems. These are solved with the method of lines and invariant imbedding.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620110410
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Notch stresses at openings and inclusions (in German), (Kerbspannungen an Ausschnitten und Einschliüssen), D. Radaj and G. Schilberth-Deutscher Verlag für Schweisstechnik, Düsseldorf 1977. No. of pages: 217, Price: DM. 98.00 (about £27 in U.K.) (1978)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 12 (1978), S. 1055-1055 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620120619
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    Paper (German National Licenses)
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